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Risk factors associated with complication following laparoscopy-assisted gastrectomy for gastric cancer: a large-scale korean multicenter study

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dc.contributor.authorKim, Min Chan-
dc.contributor.authorKim, Wook-
dc.contributor.authorKim, Hyung Ho-
dc.contributor.authorRyu, Seung Wan-
dc.contributor.authorRyu, Seong Yeob-
dc.contributor.authorSong, Kyo Young-
dc.contributor.authorLee, Hyuk Joon-
dc.contributor.authorCho, Gyu Seok-
dc.contributor.authorHan, Sang Uk-
dc.contributor.authorHyung, Woo Jin-
dc.date.accessioned2010-04-08T23:52:15Z-
dc.date.available2010-04-08T23:52:15Z-
dc.date.issued2008-07-30-
dc.identifier.citationAnn Surg Oncol. 2008; 15(10):2692-2700en
dc.identifier.issn1534-4681 (Electronic)-
dc.identifier.urihttp://hdl.handle.net/10371/62755-
dc.description.abstractBACKGROUND: The aim of this multicenter retrospective study was to establish background data for future randomized clinical trial comparing open and laparoscopy-assisted gastrectomies (LAGs). We sought to evaluate the technical feasibility of LAG by determining the morbidity and mortality and identifying corresponding predictive factors. PATIENTS AND METHODS: A retrospective multicenter study was carried out in Korea on 1,485 patients in who, LAG had been attempted for gastric cancer under the care of ten surgeons, at ten institutions, during the period spanning May 1998 to December 2005. Patient characteristics, operative outcomes, and postoperative morbidities and mortalities were analyzed. RESULTS: Overall morbidity and mortality rates were 14.0% and 0.6%, respectively. Complications included: wound problem (4.2%, n = 62), intraluminal bleeding (1.3%, n = 20), intra-abdominal abscess or fluid collection (1.3%, n = 19), anastomotic leakage (1.3%, n = 18), and intra-abdominal bleeding (1.3%, n = 18). By using multivariate analysis we found that the two most important risk factors associated with postoperative complications were presence of comorbidity in the patient and lack of experience on the part of the surgeon. CONCLUSION: LAG is a technically feasible, safe, and effective method for treating patients with gastric cancer. Extra caution in patients with comorbidities, and dedication to improving surgical proficiency in LAG, may decrease the risk of complications. Through this study, we have established the inclusion criteria for LAG. For our multicenter, prospective, randomized trials (NCT00452751), potential patients should have an American Society of Anesthesiology (ASA) score of less than 3, and surgeons performing the procedures should have experience with more than 50 cases of LAG.en
dc.language.isoenen
dc.publisherSpringer Verlagen
dc.subjectFeasibility Studiesen
dc.subjectGastrectomy/*adverse effectsen
dc.subject*Laparoscopyen
dc.subjectNeoplasm Stagingen
dc.subject*Postoperative Complicationsen
dc.subjectPrognosisen
dc.subjectRandomized Controlled Trials as Topicen
dc.subjectRetrospective Studiesen
dc.subjectRisk Factorsen
dc.subjectStomach Neoplasms/pathology/*surgeryen
dc.subjectSurvival Rateen
dc.titleRisk factors associated with complication following laparoscopy-assisted gastrectomy for gastric cancer: a large-scale korean multicenter studyen
dc.typeArticleen
dc.contributor.AlternativeAuthor김민찬-
dc.contributor.AlternativeAuthor김욱-
dc.contributor.AlternativeAuthor김형호-
dc.contributor.AlternativeAuthor류승완-
dc.contributor.AlternativeAuthor류성엽-
dc.contributor.AlternativeAuthor송교영-
dc.contributor.AlternativeAuthor이혁준-
dc.contributor.AlternativeAuthor조규석-
dc.contributor.AlternativeAuthor한상욱-
dc.contributor.AlternativeAuthor형우진-
dc.identifier.doi10.1245/s10434-008-0075-z-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Surgery (외과학전공)Journal Papers (저널논문_외과학전공)
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