Measurement of Mean Circumferential Fiber Shortening Rate Using Radionuclide Blood Pool Scan
방사선동위원소 심혈관촬영술을 이용한 평규원주단축율 측정에 관한 연구

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Lee, Myung Chul; Shin, Seong Hae; Park, Young Bae; Koh, Chang-Soon
Issue Date
Seoul National University College of Medicine
Seoul J Med 1988;29(2):149-154
Mean circumferential fiber shortening rateradionuclide blood pool scancoronary artery disease
Ejection phase indices of left ventricular performance are standard parameters
for the evaluation of myocardial contractility. Recently, ejection fraction and ejection rate are
easily obtained from radionuclide gated cardiac blood pool scan. No method, however, is
available for determining the mean circumferential fiber shortening rate (Vcf) precisely. Velocity
indices are relatively independent of alternation in resting filling pressure and volume, and
responsive to changes in heart rate. We measured the left ventricular mean circumferential fiber
shortening velocity using gamma camera interfaced to a computer after injection of radionuclide
to evaluate its significance for detecting left ventricular dysfunction, especially in patients
With coronary heart disease. Radionuclide-determined values for mean fiber shortening rate
correlated (r=0.79) with values for this index obtained from echocardiography. Left ventricular
ejection fraction correlated with mean fiber shortening rate. There was a strong relationship
between the value of mean fiber shortening rate and the severity of myocardial impairment by
the NYHA(New York Heart Association) functional class (r=0.84).
In summary, these data indicate that gated cardiac blood pool scan provides a noninvasive,
accurate and simple method to measure the mean circumferential fiber shortening rate and it
can be utilized in a variety of cardiac disorders.
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 29 No.2 (1988)
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