Age-Related Changes in Calretinin-Immunoreactive Periglomerular Cells in the Rat Main Olfactory Bulb
- Authors
- Hwang, In Koo; Yoo, Ki-Yeon; Nam, Young Sam; Choi, Jung Hoon; Seo, Kangmoon; Lee, In Se; Jung, Ju Young; Kang, Tae-Cheon; Oh, Yang-Seok; Won, Moo Ho
- Issue Date
- 2006
- Publisher
- Japanese Society of Veterinary Science
- Citation
- J. Vet. Med. Sci. 68: 465-469
- Keywords
- aging; calretinin; degeneration; periglomerular cells; SD rat
- Abstract
- The changes of calretinin (CR)-immunoreactive periglomerular cells in the glomerular layer of the main olfactory bulb (MOB) were investigated in rats differing ages from postnatal month 1 (PM 1) to PM 24. The number of cresyl violet-positive periglomerular cells was similar between PM 1 and PM 12, but they decreased slightly in the PM 24 group. The size of CR-immunoreactive periglomerular cells in the glomerular layer increased with age, while their numbers did not change significantly in the PM 6-PM 24 groups. In the PM 24 group, numbers of CR-positive periglomerular cell bodies and their processes decreased, while the size of CR-positive cell bodies in the glomeruli was larger than that of the previous groups. These results suggest that CR-immunoreactive periglomerular cells in the rat MOB are well-developed in the PM 6 group, and that periglomerular cells in the PM 24 group show poor CR-immunoreactivity compared to those in the PM 6 group.
- ISSN
- 0916-7250 (print)
1347-7439 (online)
- Language
- English
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