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Designed fabrication of multifunctional magnetic gold nanoshells and their application to magnetic resonance imaging and photothermal therapy

Cited 389 time in Web of Science Cited 414 time in Scopus
Authors
Kim, Jaeyun; Park, Sungjin; Lee, Ji Ean; Jin, Seung Min; Lee, Jung Hee; Lee, In Su; Yang, Ilseung; Kim, Jun-Sung; Kim, Seong Keun; Cho, Myung-Haing; Hyeon, Taeghwan
Issue Date
2006-11
Publisher
John Wiley & Sons
Gesellschaft Deutscher Chemiker
Citation
Angewandte Chemie - International Edition, Vol.45 No.46, pp.7754-7758
Keywords
goldmagnetic resonance imagingnanomedicinenanostructuresphotothermal therapy
Abstract
Targeting cancer: Multifunctional magnetic gold nanoshells (Mag-GNS) are prepared by coating silica spheres with gold nanoshells embedded with Fe 3O4 nanoparticles. The Fe3O4 nanoparticles allow magnetic resonance imaging (MRI) for diagnosis, and the gold nanoshells enable photothermal therapy. By attaching an antibody to the Mag-GNS by a poly(ethylene glycol) (PEG) linker, cancer cells can be targeted. (Figure Presented). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
ISSN
1433-7851
Language
English
URI
http://hdl.handle.net/10371/6479
DOI
https://doi.org/10.1002/anie.200602471
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College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Journal Papers (저널논문_화학생물공학부)
College of Engineering/Engineering Practice School (공과대학/대학원)Dept. of Chemical and Biological Engineering (화학생물공학부)Chemical Convergence for Energy and Environment (에너지환경 화학융합기술전공)Journal Papers (저널논문_에너지환경 화학융합기술전공)
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