인삼 Saponin을 투여한 마우스의 개야 활동 분석

Abstract

To examine the effect of saponin of Panax Ginseng the open-field locomotor activity and frequency of occurence of behavioral component patterns of mice were tested. 1) The locomotor activity of the two doses of Ginseng Saponin, i. e., 5mg/kg and 5Jmg/kg was significantly fewer than that of saline control throughout a 10 min. observation period. 2) Two Panax Ginseng groups displayed exploratory activity significantly more often. but reared significantly less often than did the control group. 3) The Panax Ginseng in dose of 5Jmgjkg showed significantly more often lying than that of placebo control. 4) No significant difference was found between Ginseng and control with regard to walking and grooming. It is considered that Panax Ginseng as a whole exerts an -Inhibitory influence upon spontaneous locomotor activity, while exerting a predominantly stimulant influence upon the exploratory activity.