내분비 변조에 다른 흰쥐 뇌하수체 난포 자극호르몬 세포의 변화
Studies on the FSH Granules of Rat Adenohypophysis under Various Conditions of Altered Hormonal Status

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박태규; 백상호
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서울대학교 의과대학
Seoul J Med 1974;15(3):163-174
Follicle stimulating hormone cells and its granules
of rat adenohypophysis under various status of
hormonal alteration have been studied.
To induce the alteration of endocrine condition.
gonadectomy or long term administration of estradiol
has been carried out before sacrifice. Pituitary
glands from the rats of estrous cycle and in gestation
were also studied.
Tissue sections of the glands were reacted with
specific rabbit antiserum to the ovine FSH and
followed by anti-rabbit gamma globulin labeled with
horseradish peroxidase. The enzyme wail localized
histochemically with diaminobenzidine.
Number of FSH cells was reduced after long term
administration of estradiol while castration. estrous
cycle and gestation did not affect significantly. The
most intense reactions of granules were observed in
the pituitary glands of castrated group and the
least intense reactions from the rats in estrus. Rats
from thirty days after gonadectomy and rats in
proestrus revealed well granulated FSH cells while
the rats in estrus revealed poor granulation. Only
the castrated rats showed increase of hypophyseal
weight. No FSH granules could be observed in the
adenohypophysis of new born rats.
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 15 No.3 (1974)
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