대퇴동맥 혈류양에 영향을 주는 각종인자

Abstract

1. The effects of alteration of arterial blood pressure on femoral blood flow and femoral blood flow/cardiac output ratio in the dog has been determined under condition of constant infusion of epinephrine or constant bleeding. During the period of hypertension, femoral blood flow and cardiac output increased, but total peripheral resistance, femoral vascular resistance and femoral blood flow/cardiac output ratio were not altered. During hypotension, cardiac output decreased progressively, but the decrease of femoral blood flow were relatively small comparing to the depression of arterial blood pressure. This might be due to the larger decrease of femoral vascular resistance than that of total peripheral resistance Consequently, femoral blood flow/ cardiac output ratio increased significantly. 2. The effects of alteration of arterial Pco, on femoral blood flow and femoral blood flow/cardiac output ratio has been determined under condition of hyperventilation or 5% CO,-02 gas inhalation. During the period of hyperventilation, femoral blood flow and femoral blood flow/cardiac output ratio tended to decrease. During the hypercapnea, on the contrary, femoral blood flow increased markedly. The result might be due to large decrement in femoral vascular resistance with unaltered total peripheral resistance, femoral blood flow/cardiac output ratio increased remarkably. 3. The effect of alteration of arterial blood pll on femoral blood flow and femoral blood flow/cardiac output ratio has been determined under condition of infusion of O.6M sodium bicarbonate or O.3N hydrochloric acid. During the acidosis, femoral blood flow increased. This might be due to decrease of femoral vascular resistance and increase of total peripheral resistance, in spite of decreased cardiac output. Femoral blood flow/cardiac output ratio increased eminently.