심장, 폐기능 연구에서의 의용 계통 해석학의 이용
Applications of Biomedical System Analysis to Cardiopulmonary Research

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서울대학교 의과대학
Seoul J Med 1990;21(1):87-91
Mathematical and Engineering approaches have been applied for the analysis and quantification of
biomedical research.
In this paper, the following biomedical system analysis
methods are applied to evaluate tbe cardiac
pulmonary functions:
I. Cardiac Pumping function study; (1-a) Sensitivity
and after-load independence of zero-load aortic
flow, (I-b) Relation between computed zero-load aortic
flow and cardiac muscle mechanics.
2. Study of Ventricular output flow and power;
(2-a) Non-invasive cardiac output estimation based
upon a mathematical model of the aorta, (2-b) Significance
of left ventricular pressure waveform on
changes in stroke volume during pulsatile left ventricular
bypass, (2-c) Performance criteria for optimization
of cardiac assistance.
3. Dynamic changes of cerebral blood flow and
oxygen stores to hypoxia, (3-a) Frequency-domain
Analysis of oxygen stores during hypoxia in goats,
(3-b) Dynamic characteristics of cerebral blood flow
response to sinusoidal hypoxia.
The above seven examples of cardio-pulomonary
research demonstrate the usefulness of the biomedical
system analysis for the evaluation of transient phenomena
and dynamic characteristics of the physiological
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 21 No.1 (1980)
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