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Correlation of immunohistochemical characteristics of the craniomandibular joint with the degree of mandibular lengthening in rabbits
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Su-Gwan | - |
dc.contributor.author | Park, Ju-Cheol | - |
dc.contributor.author | Kang, Dong-Wan | - |
dc.contributor.author | Kim, Byung-Ock | - |
dc.contributor.author | Yoon, Jung-Hoon | - |
dc.contributor.author | Cho, Se-Inn | - |
dc.contributor.author | Choe, Han-Cheol | - |
dc.contributor.author | Bae, Chun-Sik | - |
dc.date.accessioned | 2010-05-17T11:09:08Z | - |
dc.date.available | 2010-05-17T11:09:08Z | - |
dc.date.issued | 2003-10 | - |
dc.identifier.citation | J Oral Maxillofac Surg 61:1189-1197 | en |
dc.identifier.issn | 0278-2391 | - |
dc.identifier.uri | https://hdl.handle.net/10371/66622 | - |
dc.description.abstract | Purpose: This study examined immunohistochemical changes in the craniomandibular joints of rabbits
after distraction osteogenesis following mandibular corticotomy. Materials and Methods: The experimental animals (n 8) were divided into 3 groups that underwent 2, 3.5, and 5 mm of unilateral distraction osteogenesis (groups 1, 2, and 3, respectively). After corticotomy of the left mandibular body and a 7-day healing period, a second operation was performed to expose the device. Distraction was then performed at the rate of 0.5 mm/d. A 14-day consolidation period was allowed after the distraction was complete. Changes in cartilage, osteoblast activity, and osteoclast activity were then examined. Results: The differentiation and proliferation of cartilage increased in groups 1 and 2, were highest in group 2, and decreased in group 3. Group 2 also showed the greatest increase in the width of the hypertrophic chondrocyte layer. Relative to the control group, osteoclast activity was only somewhat higher in groups 1 and 2 but was significantly higher in group 3. Osteoblast activity was significantly higher in groups 1 and 2 than in the control group. However, the osteoblast activity in group 3 was slightly lower than that in group 2. At the time of unilateral mandibular distraction, no degenerative changes of the temporomandibular joint were observed in groups 1 or 2, but bone resorption was observed in group 3. Conclusions: The unilateral mandibular distraction of 2 or 3.5 mm was acceptable in that no degenerative changes of the temporomandibular joint were observed on either the distraction or the nondistraction sides. Five millimeters of distraction might be beyond physiologic limits. | en |
dc.description.sponsorship | This work was supported by Grant 2000-1-205-012-2 from the Basic
Research Program of the Korea Science and Engineering Foundation. | en |
dc.language.iso | en | - |
dc.publisher | Elsevier | en |
dc.title | Correlation of immunohistochemical characteristics of the craniomandibular joint with the degree of mandibular lengthening in rabbits | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김수관 | - |
dc.contributor.AlternativeAuthor | 박주철 | - |
dc.contributor.AlternativeAuthor | 강동완 | - |
dc.contributor.AlternativeAuthor | 김병옥 | - |
dc.contributor.AlternativeAuthor | 윤정훈 | - |
dc.contributor.AlternativeAuthor | 조세인 | - |
dc.contributor.AlternativeAuthor | 최한철 | - |
dc.contributor.AlternativeAuthor | 배준식 | - |
dc.identifier.doi | 10.1016/S0278-2391(03)00681-5 | - |
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