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Pregnancy outcomes of different methods for multifetal pregnancy reduction: a comparative study

Cited 6 time in Web of Science Cited 7 time in Scopus
Authors
Lee, Jung Ryeol; Ku, Seung-Yup; Jee, Byung Chul; Suh, Chang Suk; Kim, Ki Chul; Kim, Seok Hyun
Issue Date
2008-02-28
Publisher
Korean Academy of Medical Sciences
Citation
J Korean Med Sci. 2008; 23(1): 111-6
Keywords
AdultFemaleHumansPotassium Chloride/therapeutic usePregnancy*Pregnancy OutcomePregnancy Reduction, Multifetal/*methodsRetrospective Studies
Abstract
The purpose of this study was to evaluate the outcomes of various methods of multifetal pregnancy reduction (MFPR) and to determine which method produces better outcomes. One hundred and forty-eight patients with multiple pregnancies resulting from assisted reproduction programs and underwent MFPR were included. According to the use of potassium chloride (KCl), patients were divided into 'KCl', and 'non- KCl' groups, and based on gestational age at the time of procedures, patients were divided into 'Early' (before 8 weeks of gestation) and 'Late' (at 8 weeks or later) groups. Firstly, to clarify the effect of each component of MFPR procedure, data were analyzed between 'KCl' and 'non-KCl' groups, and between 'Early' and 'Late' groups with adjustments. Secondly, comparison between 'Early, non-KCl' and 'Late, KCl' groups was performed to evaluate the combinative effect of both components. Non-KCl groups showed a significantly higher take-home-baby rate, and lower risk of extreme prematurity and preterm premature rupture of membranes (PPROM) than KCl groups. Early groups showed a lower immediate loss rate than Late groups. As compared with 'Late, KCl' group, 'Early, non-KCl' group was superior in terms of immediate loss, pregnancy loss, take-home-baby, and PPROM rates. Our data suggest that the 'early, non-KCl' method may be a better option for MFPR.
ISSN
1011-8934 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18303209

http://hdl.handle.net/10371/67665
DOI
https://doi.org/10.3346/jkms.2008.23.1.111
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College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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