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Expression of volume-activated anion channels in exocrine acinar cells

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Authors
Park, Kyungpyo; Majid, Aneela
Issue Date
2000
Publisher
Korean Academy of Medical Sciences
Citation
Journal of Korean Medical Science 2000; 15: S61-S62
Keywords
Chloride ChannelsVolume RegulationAcinar Cells
Abstract
Volume-sensitive anion channels (Iclswell)are expressed in most mammalian cells (1). The molecular identity of Iclswell is not known, however, several candidate proteins have been proposed including: p-glycoprotein, pIcln, CIC-2 and CIC-3(2). The properties of CIC-3 make it one of the most likely candidate proteins, e.g. it has a structure which is very similar to that of know Cl- channels (CIC-0 and CIC-1), and it produces an outward-rectifying Cl- conductance when expressed in Xenopus oocytes or mammalian cell lines (3).
ISSN
1011-8934
Language
English
URI
http://hdl.handle.net/10371/67672
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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