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Castleman disease presenting with jaundice: a case with the multicentric hyaline vascular variant

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Authors
Park, Jun Bean; Hwang, Jin Hyeok; Kim, Haeryoung; Choe, Hyung Sim; Kim, Yu Kyeong; Kim, Hong Bin; Bang, Soo-Mee
Issue Date
2007-07-10
Publisher
Korean Association of Internal Medicine
Citation
Korean J Intern Med. 22(2):113-117
Keywords
Abdominal Pain/etiologyAdrenal Cortex Hormones/therapeutic useBiopsyGiant Lymph Node Hyperplasia/*diagnosis/drug therapy/pathologyHumansJaundice/*complicationsMaleMiddle AgedPositron-Emission TomographyTomography, X-Ray ComputedVascular Diseases/*diagnosis/pathology
Abstract
Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A previous healthy 50 year-old man was hospitalized for right upper quadrant (RUQ) abdominal pain. He had jaundice and a 1 cm-sized lymph node in the right supraclavicular area. Pancreas and biliary computed tomography (CT) showed masses at the right renal hilum and peripancreatic areas. Positron emission tomography (PET) showed widespread systemic lymphadenopathy. Excisional biopsy of the right supraclavicular node revealed a hyaline vascular variant of CD. Corticosteroid therapy was started and the extent of disease decreased. We here report a case of multicentric CD, the hyaline vascular variant, presenting with jaundice, diagnosed by excisional biopsy and successfully treated with corticosteroids.
ISSN
1226-3303 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17616028

http://hdl.handle.net/10371/67815
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College of Medicine/School of Medicine (의과대학/대학원)Nuclear Medicine (핵의학전공)Journal Papers (저널논문_핵의학전공)
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