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Serum soluble CD163 and interleukin-6 levels in women with ovarian endometriomas
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jee, Byung Chul | - |
dc.contributor.author | Suh, Chang Suk | - |
dc.contributor.author | Kim, Seok Hyun | - |
dc.contributor.author | Moon, Shin Yong | - |
dc.date.accessioned | 2010-06-30T03:19:45Z | - |
dc.date.available | 2010-06-30T03:19:45Z | - |
dc.date.issued | 2008-03-04 | - |
dc.identifier.citation | Gynecol Obstet Invest. 2008;66(1):47-52 | en |
dc.identifier.issn | 1423-002X (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18311079 | - |
dc.identifier.uri | http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=000119091&Ausgabe=234533&ProduktNr=223845&filename=000119091.pdf | - |
dc.identifier.uri | https://hdl.handle.net/10371/68039 | - |
dc.description.abstract | BACKGROUND: CD163 is a hemoglobin scavenger receptor exclusively expressed in the monocyte-macrophage system and its soluble form (sCD163) has not yet been studied as a serum marker in women with endometriosis. The purpose of this study was to evaluate whether serum levels of sCD163 and interleukin-6 (IL-6) could be possible markers for ovarian endometriomas discriminating adnexal benign cystic tumors. METHODS: The concentrations of sCD163 and IL-6 were determined using commercial ELISA kits in frozen sera collected from 95 women prior to surgery for adnexal benign cystic tumors: 44 with ovarian endometriomas, 24 with mature cystic teratomas, 10 with mucinous cystadenomas, 8 with serous cystadenomas and 9 with parovarian cysts. Serum levels of CA-125 were also recorded preoperatively. The volume of cysts was evaluated in women with ovarian endometriomas. RESULTS: The serum levels of sCD163 and IL-6 were not significantly different among the women with various adnexal benign cystic tumors. In patients with endometriomas (n = 44), the levels were similar to those with nonendometriotic benign cystic tumors (n = 51): 3,431.7 +/- 343.9 vs. 3,231.0 +/- 391.7 ng/ml for sCD163 and 5.3 +/- 0.9 vs. 12.9 +/- 4.0 pg/ml for IL-6 (mean +/- SEM). No correlation was noted between serum levels of two markers with volume of endometriomas. CONCLUSION: Our findings suggest that serum levels of sCD163 as well as IL-6 are not useful markers for ovarian endometriomas. | en |
dc.language.iso | en | en |
dc.publisher | Karger | en |
dc.subject | Adult | en |
dc.subject | Antigens, CD/*blood | en |
dc.subject | Antigens, Differentiation, Myelomonocytic/*blood | en |
dc.subject | Biological Markers/blood | en |
dc.subject | CA-125 Antigen/blood | en |
dc.subject | Endometriosis/*blood | en |
dc.subject | Enzyme-Linked Immunosorbent Assay | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Interleukin-16/*blood | en |
dc.subject | Middle Aged | en |
dc.subject | Ovarian Diseases/*blood | en |
dc.subject | Receptors, Cell Surface/*blood | en |
dc.title | Serum soluble CD163 and interleukin-6 levels in women with ovarian endometriomas | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 지병철 | - |
dc.contributor.AlternativeAuthor | 서창석 | - |
dc.contributor.AlternativeAuthor | 김석현 | - |
dc.contributor.AlternativeAuthor | 문신용 | - |
dc.identifier.doi | 10.1159/000119091 | - |
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