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Clinical outcomes and patency of self-expanding metal stents in patients with malignant upper gastrointestinal obstruction

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Authors
Im, Jong Pil; Kang, Jung Mook; Kim, Sang Gyun; Kim, Joo Sung; Jung, Hyun Chae; Song, In Sung
Issue Date
2007-09-07
Publisher
Springer Verlag
Citation
Dig Dis Sci. 53(4):938-945
Keywords
AgedCohort StudiesEquipment Design*Esophagogastric JunctionFemaleGastric Outlet Obstruction/*etiology/pathology/*surgeryGastrointestinal Neoplasms/mortality/*pathology/surgeryHumansMaleMetalsMiddle AgedRetrospective StudiesRisk Factors*StentsTreatment Outcome
Abstract
This study was performed to evaluate clinical outcomes and factors associated with patency of self-expanding metal stents (SEMS) in patients with malignant upper gastrointestinal (UGI) obstruction. In 83 patients with malignant UGI obstruction, 118 SEMS placements were performed. Obstruction sites were esophagus/gastro-esophageal junction (GEJ) and gastric outlet (GO) in 41 and 42 patients, respectively. Technical success was achieved in 99.2% and clinical success in 90.5%, with no procedure-related complications. Re-obstruction and migration occurred in 38.1% during a mean follow-up of 137 days; both occurred significantly more often with GO than esophageal/GEJ obstruction (49.2% vs 23.9%). Patency rates of esophageal/GEJ obstruction were 93.5, 78.1 and 67.0% at 30, 90 and 180 days, respectively, and were significantly higher than those of GO obstruction-71.7, 51.8 and 32.5%. Palliative chemotherapy or radiation therapy was not associated with stent patency. Endoscopic SEMS placement is a safe and effective palliative treatment for malignant UGI obstruction, and complications or stent patency differed according to obstruction site.
ISSN
0163-2116 (Print)
http://dx.doi.org/10.1007/s10620-007-9967-1
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17805967
http://www.springerlink.com/content/m04m50k8n44u4607/fulltext.pdf
Language
English
URI
http://hdl.handle.net/10371/68208
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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