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Endoscopic vitrectomy improves outcomes of Seoul-type keratoprosthesis exchange in rabbit model

Cited 4 time in Web of Science Cited 7 time in Scopus
Authors
Lee, Sang-Mok; Kim, Mee-Kum; Oh, Joo Youn; Heo, Jang-Won; Shin, Mi-Sun; Lee, Moo-Suk; Wee, Won-Ryang; Lee, Jin-Hak
Issue Date
2008-10-03
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Citation
Invest Ophthalmol Vis Sci. 2008;49(10):4407-4411
Keywords
Animals*Artificial Organs*CorneaEndoscopy/*methodsMaleModels, AnimalProsthesis ImplantationRabbitsTreatment OutcomeVitrectomy/*methodsVitreous Body/*surgery
Abstract
PURPOSE: To investigate the efficacy of an endoscopic vitrectomy in Seoul-type keratoprosthesis (S-Kpro) exchange procedures. METHODS: Nine S-Kpro-implanted rabbit eyes were enrolled in the S-Kpro exchange. Six eyes underwent an antecedent vitrectomy by an endoscopic system and then the S-Kpro exchange (endoscopy group). In the other three eyes, previously placed S-Kpros were removed, and a conventional vitrectomy was performed using the Eckardt keratoprosthesis, followed by an implantation of new S-Kpros (Eckardt group). All eyes were evaluated with slit lamp biomicroscopy and ultrasonography weekly to evaluate the time up to the development of the total retinal detachment (RD). RESULTS: Vitreous traction membranes were found around the prolene haptics of the fixation sites in all the S-Kpro implanted rabbits; they were excised precisely through an endoscopic view in the endoscopy group. The mean survival time up to the RD development was 9.75 +/- 4.70 weeks in the endoscopy group. In contrast, total retinal detachment or dialysis over 180 degrees developed during surgery in all three eyes in the Eckardt group. CONCLUSIONS: Antecedent endoscopic vitrectomy was safe and effective for the S-Kpro exchange in a rabbit model by removing the vitreous traction near the haptics before the exchange procedures.
ISSN
1552-5783 (Electronic)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18829860

http://www.iovs.org/cgi/reprint/49/10/4407.pdf

http://hdl.handle.net/10371/68252
DOI
https://doi.org/10.1167/iovs.08-1802
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College of Medicine/School of Medicine (의과대학/대학원)Ophthalmology (안과학전공)Journal Papers (저널논문_안과학전공)
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