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Diagnostic accuracy of CT-guided core biopsy of ground-glass opacity pulmonary lesions
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Tae Jung | - |
dc.contributor.author | Lee, Jae-Ho | - |
dc.contributor.author | Lee, Choon-Taek | - |
dc.contributor.author | Jheon, Sang Hoon | - |
dc.contributor.author | Sung, Sook Whan | - |
dc.contributor.author | Chung, Jin-Haeng | - |
dc.contributor.author | Lee, Kyung Won | - |
dc.date.accessioned | 2010-07-06T23:18:56Z | - |
dc.date.available | 2010-07-06T23:18:56Z | - |
dc.date.issued | 2007-12-21 | - |
dc.identifier.citation | AJR Am J Roentgenol. 2008; 190(1):234-239 | en |
dc.identifier.issn | 1546-3141 (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18094317 | - |
dc.identifier.uri | http://www.ajronline.org/cgi/reprint/190/1/234.pdf | - |
dc.identifier.uri | https://hdl.handle.net/10371/68352 | - |
dc.description.abstract | OBJECTIVE: The purpose of our study was to evaluate the accuracy of CT-guided percutaneous core biopsy of ground-glass opacity (GGO) pulmonary lesions. MATERIALS AND METHODS: The study included 50 patients (24 men, 26 women; age range, 43-78 years) who had a GGO pulmonary lesion and underwent CT-guided core biopsy. Diagnostic accuracy was compared between two groups according to lesion size (< 2 cm vs > or = 2 cm) and GGO component (> 90% vs 50-90%). Each case was reviewed for complications, including pneumothorax, thoracostomy tube insertion, and hemoptysis. RESULTS: Malignancy was finally diagnosed in 33 patients, including three who underwent repeated biopsies, with 33 true-positive and three false-negative findings for an overall sensitivity of 92% (33/36). A benign lesion was finally diagnosed in 10 patients with one false-positive result, for a specificity of 90%. Two benign lesions without confirmative diagnosis because of loss of follow-up and five nondiagnostic samples were excluded from the calculations of sensitivity, specificity, and diagnostic accuracy. The overall diagnostic accuracy was 91%, with a positive predictive value of 97% and a negative predictive value of 75%. Sensitivity and accuracy were not significantly different between the two groups of lesion size and GGO components (p = 0.0491). Ten (18%) patients had pneumothorax, with one (2%) requiring placement of a thoracostomy tube. Mild hemoptysis occurred in seven (13%) patients. CONCLUSION: CT-guided core biopsy of GGO lesions can yield high diagnostic accuracy and acceptable complication rates approaching those of solid lesions. | en |
dc.language.iso | en | en |
dc.publisher | American Roentgen Ray Society | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Biopsy/*methods | en |
dc.subject | Diagnosis, Differential | en |
dc.subject | False Negative Reactions | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Lung Diseases/diagnosis/pathology | en |
dc.subject | Lung Neoplasms/*pathology/*radiography | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Precancerous Conditions/*pathology/*radiography | en |
dc.subject | Predictive Value of Tests | en |
dc.subject | Retrospective Studies | en |
dc.subject | Sensitivity and Specificity | en |
dc.subject | Tomography, X-Ray Computed/*methods | en |
dc.title | Diagnostic accuracy of CT-guided core biopsy of ground-glass opacity pulmonary lesions | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김태정 | - |
dc.contributor.AlternativeAuthor | 이재호 | - |
dc.contributor.AlternativeAuthor | 이춘택 | - |
dc.contributor.AlternativeAuthor | 전상훈 | - |
dc.contributor.AlternativeAuthor | 성숙환 | - |
dc.contributor.AlternativeAuthor | 정진행 | - |
dc.contributor.AlternativeAuthor | 이경원 | - |
dc.identifier.doi | 10.2214/AJR.07.2441 | - |
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