S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
Analysis of spinal cord proteome in the rats with mechanical allodynia after the spinal nerve injury
- Lee, Sang Chul; Yoon, Tai Gyoon; Yoo, Yong-Il; Bang, Yung-Jue; Kim, Hae-Yeong; Jeoung, Doo-Il; Kim, Hyun Jeong
- Issue Date
- Springer Verlag
- Biotechnology Letters 25: 2071–2078
- Proteome analysis was carried out to identify the proteins associated with neuropathic pain after peripheral nerve injury. Five proteins displayed different expression levels among three groups of rats. Among these proteins, creatine kinase B expression level was lower in the pain-positive rats compared to the sham or pain-negative rats. Therefore, a lower creatine kinase B expression level may be important in the development and maintenance of neuropathic pain.
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