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Synergistic inhibitory effect of cationic peptides and antimicrobial agents on the growth of oral streptococci

Cited 17 time in Web of Science Cited 19 time in Scopus
Authors

Kim, Kack-Kyun; Kim, Sukwon S; Kim, Sunkyu; Kim, Eunshin; Hyun, Byungkuk; Lee, Byeong Jae

Issue Date
2003
Publisher
Karger
Citation
Caries Research 2003;37:425-430
Abstract
Although chlorhexidine is one of the most efficacious antimicrobial agents used for the prevention of dental caries, side effects limit its application. The effects of gaegurin 6 (GGN6), an animal-derived cationic peptide, and its derivatives PTP6 and PTP12 on the growth of oral streptococci were investigated to assess the potential of these agents for use in the prevention of dental caries. The minimal inhibitory concentrations of the peptides for inhibition of the growth of oral streptococci <(Streptococcus mutans, S. sobrinus, S. sanguis
ISSN
0008-6568
Language
English
URI
https://hdl.handle.net/10371/69600
DOI
https://doi.org/10.1159/000073394
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