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Reconstruction of human hard-palate mucosal epithelium on
Cited 22 time in
Web of Science
Cited 26 time in Scopus
- Authors
- Issue Date
- 2000-02
- Publisher
- Elsevier
- Citation
- Journal of Dermatological Science 2000;22:117-124
- Keywords
- Hard-palate ; De-epidermized dermis ; Three-dimensional culture
- Abstract
- Artificial hard-palate mucosa equivalents were reconstructed using keratinocytes derived from normal human hard-palate and de-epidermized dermis. Reconstructed hard-palate mucosal epithelium formed in three-dimensional culture was compared to native hard-palate mucosal epithelium and reconstructed oral buccal mucosal epithelium with regard to keratin expression. Artificial hard-palate mucosal epithelium reconstructed in medium with delipidized serum showed a differentiation pattern similar to that of hard-palate epithelium in vivo. The present study also confirmed that keratinocytes derived from hard-palate mucosa are intrinsically different from those of nonkeratinizing oral surfaces.
- ISSN
- 0923-1811
- Language
- English
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