Mesenchymal Hamartoma of the Liver
간의 간엽성 과오종

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Lee, Soong Deok; Chi, Je G.; Lee, Chang Youn
Issue Date
Seoul National University College of Medicine
Seoul J Med 1990;31(4):273-279
Mesenchymal hamartomaLiverCystic tumorCongenital tumorHamartoma
Mesenchymal hamartoma of the liver is an uncommon benign lesion that
appears as a large abdominal mass, almost exclusively in the first 2 years of life. It
has been believed that this lesion is not a true neoplasm but rather a kind of hamartomatous
lesion arising from the connective tissue of the portal tracts at some point in
their development. Minor components of liver cells and bile ducts are considered a
result of entrapment.
We report a case of typical cystic mesenchymal hamartoma in a 17-month-old boy
who first presented with an abdominal mass at 7 months of age. The tumor was located
in the right lobe, 17 cm in maximum diameter, and was largely cystic and partly solid,
The cysts were multiloculated and lined by a single layer of tall columnar partly ciliated
epithelium, and the irregular admixture of mature liver cell islands and intervening
loose myxoid stroma was evident. Electronmicroscopic study revealed that the lining
epithelium was the same as that of the bile duct, and the liver cell element was so
mature that it couldn't be differentiated from normal hepatocytes. The stroma cell resembled
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 31 No.4 (1990)
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