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Effect of Mechanical Deformation on in Vitro Calcification of Segmented Polyurethane

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Authors
Suh, Soo Won; Han, Dong Keun; Kim, Young Ha; Min, Byoung Goo
Issue Date
1994-12
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med 1994;35(4):275-280
Keywords
CalcificationBiomaterialMechanical deformation ElongationArtificial organ
Abstract
To investigate why calcification is accelerated by mechanical flexure,
in vitro calcification of segmented polyurethane (SPU) under static elongation and
dynamic mechanical flexure was performed. After the calcification period, the amount
of calcium deposition was increased by elongation, but the amount of calcium
deposition per unit area of the elongated surface was relatively smaller as compared
to that of the severe flexing area. Although the surface calcium concentration of the
elongated SPU was relatively smaller than the flexed area, there was the increase of
surface area by the elongation. The total amount of deposited calcium on the elongated
SPU was increased as it is reduced to the original surface area. Therefore, the
results reveal that certain changes of surface properties by the Mechanical deformation
accelerate the calcium deposition onto the surface and the enlargement of
surface area by the mechanical deformation results in the heavy calcification of the
severe flexing area in the SPU.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/7357
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 35 No.4 (1994)
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