Primary Intramedullary Neuroblastoma in Adult

Abstract

Primary neuroblastoma in the central nervous system(CNS) is unusual tumor in adult, and primary intramedullary neuroblastoma is extremely rare. The authors report a case of 36-year-old woman presenting with pain in the right anterior chest wall and weakness of the right lower extremity. An upper thoracic intraspinal mass was revealed on magnetic resonance image. On operation, the demarcation plane of the tumor was good and enabled a total removal of the subpially located intramedullary mass. Histopathological examination revealed neuroblastoma. After surgery with whole spinal irradiation, the patient was followed up for one year. There was no evidence of local recurrence radiologically and clinically. However fifteen months after the surgery, multiple metastases to the breast, lung, Iioer and brain occurred.