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Microfluidic approaches for gene delivery and gene therapy

Cited 43 time in Web of Science Cited 45 time in Scopus
Authors
Kim, Jungkyu; Hwang, Inseong; Chung, Taek Dong; Britain, Derek; Sun, Yu; Kim, Deok-Ho
Issue Date
2011
Publisher
ROYAL SOC CHEMISTRY
Citation
LAB ON A CHIP; Vol.11 23; 3941-3948
Abstract
Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and optimization of multiple processes and techniques used in gene transfection and the production of gene and drug transporters. Traditional non-viral gene transfection methods, such as electroporation, microinjection and optical gene transfection, are improved from the use of innovative microfluidic systems. Additionally, microfluidic systems have also made the production of many viral and non-viral vectors controlled, automated, and reproducible. In summary, the development and application of microfluidic systems are producing increased efficiency in gene delivery and promise improved gene therapy results.
ISSN
1473-0197
Language
English
URI
http://hdl.handle.net/10371/74933
DOI
https://doi.org/10.1039/c1lc20766k
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College of Natural Sciences (자연과학대학)Dept. of Chemistry (화학부)Journal Papers (저널논문_화학부)
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