SHERP

External-beam Co-60 radiotherapy for canine nasal tumors: A comparison of survival by treatment protocol

Cited 0 time in webofscience Cited 0 time in scopus
Authors
Yoon, Junghee; Feeney, D.A.; Jessen, C.R.; Walter, P.A.
Issue Date
2007-10-24
Publisher
Elsevier
Citation
Res. Vet. Sci. 84, 140-149
Keywords
DogNasalNeoplasmRadiotherapy protocolSurvival
Abstract
A retrospective analysis of survival times in dogs with intranasal tumors was performed comparing those treated using hypofractionated or full course Co-60 radiotherapy protocols alone or with surgical adjuvant therapy and those receiving no radiation treatment. One hundred thirty-nine dogs presented to the University of Minnesota Veterinary Medical Center for treatment of histologically-confirmed nasal neoplasia between July 1983 and October 2001 met the criteria for review. Statistically analyzed parameters included age at diagnosis, tumor histologic classification, fractionation schedule (number of treatments, and number of treatment days/week) (classified as hypofractionated if 2 or less treatments/week); calculated minimum tumor dose/fraction; calculated total minimum tumor dose (classified as hypofractionated if less than 37 Gy in six or fewer fractions); number of radiotherapy portals, a treatment gap of more than 7 days in a full course (3–5 treatments/week, 3–3.5 week treatment time) radiotherapy protocol, the influence of eye shields on survival following single portal DV fields, the survey radiographic extent of the disease, and the presence or absence of cytoreductive surgery. There was a significant relationship only between protocols using 3 or more treatments/week and at least 37 Gy cumulative minimum tumor dose and survival. However, there was no significant relationship between either total minimum tumor dose or dose/fraction and survival and there were no significant relationships between survival and any of the other variables analyzed including tumor histologic type.
ISSN
0034-5288
Language
English
URI
http://hdl.handle.net/10371/7517
DOI
https://doi.org/10.1016/j.rvsc.2007.03.004
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse