Publications
Detailed Information
Differences in Circulating Dendritic Cell Subtypes in Pregnant Women, Cord Blood and Healthy Adult Women
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Sue | - |
dc.contributor.author | Jang, Jee Young | - |
dc.contributor.author | Yoon, Jong Hyun | - |
dc.contributor.author | Roh, Eun Youn | - |
dc.contributor.author | Kim, Serim | - |
dc.contributor.author | Choi, Young Sook | - |
dc.contributor.author | Kim, Soo-Hyun | - |
dc.contributor.author | Song, Eun Young | - |
dc.contributor.author | Kim, Sun-Jong | - |
dc.contributor.author | Choi, Ji-Da | - |
dc.contributor.author | Yun, Yeomin | - |
dc.contributor.author | Han, Kyou Sup | - |
dc.contributor.author | Kim, Jong Seung | - |
dc.date.accessioned | 2012-05-23T00:45:03Z | - |
dc.date.available | 2012-05-23T00:45:03Z | - |
dc.date.issued | 2009-10 | - |
dc.identifier.citation | JOURNAL OF KOREAN MEDICAL SCIENCE; Vol.24 5; 853-859 | ko_KR |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76285 | - |
dc.description.abstract | Different subtypes of dendritic cells (DC) influence the differentiation of naive T lymphocytes into T helper type 1 (Th1) and Th2 effector cells. We evaluated the percentages of DC subtypes in peripheral blood from pregnant women (maternal blood) and their cord blood compared to the peripheral blood of healthy non pregnant women (control). Circulating DC were identified by flow cytometry as lineage (CD3, CD14, CD16, CD19, CD20, and CD56)-negative and HLA-DR-positive cells. Subtypes of DC were further characterized as myeloid DC (CD11c(+)/CD123(+/-)), lymphoid DC (CD11c(-)/CD123(+++)) and less differentiated DC (CD11c(-)/CD123(+/-)). The frequency of DC out of all nucleated cells was significantly lower in maternal blood than in control (P<0.001). The ratio of myeloid DC/lymphoid DC was significantly higher in maternal blood than in control (P<0.01). HLA-DR expressions of myeloid DC as mean fluorescence intensity (MFI) were significantly less in maternal blood and in cord blood than in control (P<0.001, respectively). The DC differentiation factors, TNF-alpha and GM-CSF, released from mononuclear cells after lipopolysaccharide stimulation were significantly lower in maternal blood than in control (P<0.01). The distribution of DC subtypes was different in maternal and cord blood from those of non-pregnant women. Their role during pregnancy remains to be determined. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | ko_KR |
dc.subject | Cord Blood | ko_KR |
dc.subject | Dendritic Cells | ko_KR |
dc.subject | Flow Cytometry | ko_KR |
dc.subject | Pregnancy | ko_KR |
dc.title | Differences in Circulating Dendritic Cell Subtypes in Pregnant Women, Cord Blood and Healthy Adult Women | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 신수 | - |
dc.contributor.AlternativeAuthor | 노은윤 | - |
dc.contributor.AlternativeAuthor | 한규섭 | - |
dc.contributor.AlternativeAuthor | 김종승 | - |
dc.contributor.AlternativeAuthor | 윤종현 | - |
dc.contributor.AlternativeAuthor | 장지영 | - |
dc.contributor.AlternativeAuthor | 김세림 | - |
dc.contributor.AlternativeAuthor | 송은영 | - |
dc.contributor.AlternativeAuthor | 김선종 | - |
dc.contributor.AlternativeAuthor | 김수현 | - |
dc.contributor.AlternativeAuthor | 최지다 | - |
dc.contributor.AlternativeAuthor | 최영숙 | - |
dc.contributor.AlternativeAuthor | 윤여민 | - |
dc.identifier.doi | 10.3346/jkms.2009.24.5.853 | - |
dc.citation.journaltitle | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.description.citedreference | Adams KM, 2007, PLACENTA, V28, P378, DOI 10.1016/j.placenta.2006.07.003 | - |
dc.description.citedreference | Gerrits JH, 2007, TRANSPL IMMUNOL, V17, P169, DOI 10.1016/j.trim.2006.11.006 | - |
dc.description.citedreference | Averill L, 2007, CLIN IMMUNOL, V123, P40, DOI 10.1016/j.clim.206.12.001 | - |
dc.description.citedreference | Aldebert D, 2007, J REPROD IMMUNOL, V73, P11, DOI 10.1016/j.jri.2006.05.002 | - |
dc.description.citedreference | Pinzon-Charry A, 2005, NEOPLASIA, V7, P1123, DOI 10.1593/neo.05448 | - |
dc.description.citedreference | ADAMS S, 2005, J CLIN IMMUNOL, V25, P177 | - |
dc.description.citedreference | Beckebaum S, 2004, CLIN CANCER RES, V10, P7260 | - |
dc.description.citedreference | Darmochwal-Kolarz D, 2004, IMMUNOL LETT, V91, P71, DOI 10.1016/j.imlet.2003.11.006 | - |
dc.description.citedreference | WEGMANN TG, 1993, IMMUNOL TODAY, V14, P353 | - |
dc.description.citedreference | Piccinni MP, 1996, IMMUNOL RES, V15, P141 | - |
dc.description.citedreference | Sorg RV, 1999, BLOOD, V93, P2302 | - |
dc.description.citedreference | Adkins B, 1999, IMMUNOL TODAY, V20, P330 | - |
dc.description.citedreference | Ueda Y, 2003, HUM IMMUNOL, V64, P1144 | - |
dc.description.citedreference | Luppi P, 2003, VACCINE, V21, P3352, DOI 10.1016/S0264-410X(03)00331-1 | - |
dc.description.citedreference | Steinman RM, 2003, APMIS, V111, P675 | - |
dc.description.citedreference | Hagendorens MM, 2003, CLIN EXP ALLERGY, V33, P633 | - |
dc.description.citedreference | Szabolcs P, 2003, STEM CELLS, V21, P296 | - |
dc.description.citedreference | Almeida J, 1999, CLIN EXP IMMUNOL, V118, P392 | - |
dc.description.citedreference | Kadowaki N, 2000, J EXP MED, V192, P219 | - |
dc.description.citedreference | MOSMANN TR, 1989, ANNU REV IMMUNOL, V7, P145 | - |
dc.description.citedreference | Langrish CL, 2002, CLIN EXP IMMUNOL, V128, P118 | - |
dc.description.citedreference | Schibler KR, 2002, ACTA PAEDIATR, V91, P9 | - |
dc.description.citedreference | Uchida Y, 2001, J ALLERGY CLIN IMMUN, V108, P1005, DOI 10.1067/mai.2001.119741 | - |
dc.description.citedreference | Summers KL, 2001, AM J PATHOL, V159, P285 | - |
dc.description.citedreference | Borras FE, 2001, BRIT J HAEMATOL, V113, P925 | - |
dc.description.citedreference | Liu E, 2001, BRIT J HAEMATOL, V113, P240 | - |
dc.description.citedreference | Cella M, 2000, NAT IMMUNOL, V1, P305 | - |
dc.description.tc | 2 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.