Browse

Usefulness of routine lumbar puncture in non-HIV patients with latent syphilis of unknown duration

DC Field Value Language
dc.contributor.authorChoe, Pyoeng Gyun-
dc.contributor.authorSong, Jin Su-
dc.contributor.authorJeon, Jae Hyun-
dc.contributor.authorSong, Kyoung-Ho-
dc.contributor.authorPark, Wan Beom-
dc.contributor.authorPark, Sang Won-
dc.contributor.authorOh, Myoung-Don-
dc.contributor.authorKim, Hong Bin-
dc.contributor.authorKim, Nam Joong-
dc.contributor.authorPark, Kyoung Un-
dc.date.accessioned2012-05-23T01:52:33Z-
dc.date.available2012-05-23T01:52:33Z-
dc.date.issued2010-05-
dc.identifier.citationSEXUALLY TRANSMITTED INFECTIONS; Vol.86 1; 39-40ko_KR
dc.identifier.issn1368-4973-
dc.identifier.urihttp://hdl.handle.net/10371/76302-
dc.description.abstractObjectives To evaluate the usefulness of routine lumbar puncture in non-HIV patients with untreated latent syphilis. Methods We conducted a prospective study in Seoul National University Bundang Hospital from May 2003 to December 2005. Participants in routine health check-ups of the healthcare system were screened for serological evidence of syphilis by the Treponema pallidum particle agglutination (TPPA) test. Lumbar puncture was performed, with consent, on untreated latent syphilitic patients. Neurosyphilis was defined as positivity for cerebrospinal fluid Venereal Disease Research Laboratory (CSF VDRL) or pleocytosis with positivity for CSF TPPA or elevation of CSF protein with IgG index exceeding 0.85. Results Of 21 507 participants, 282 (1.4%) had serological evidence of syphilis. 117 (41%) of these had a history of syphilis treatment and 2 were seropositive for HIV. Among the 163 non-HIV patients with untreated latent syphilis, 70 (43%) underwent lumbar puncture. All the patients had VDRL titres less than 1:16. Abnormal neurological signs or symptoms were present in eight (11%) patients. CSF abnormalities were seen in 57 (81%), but no patient (0%, 95% CI 0 to 6.2) was diagnosed with neurosyphilis. Conclusions The estimated prevalence of neurosyphilis among non-HIV patients with untreated latent syphilis and serum VDRL < 1:16, was below 6.2%.ko_KR
dc.language.isoenko_KR
dc.publisherB M J PUBLISHING GROUPko_KR
dc.titleUsefulness of routine lumbar puncture in non-HIV patients with latent syphilis of unknown durationko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor박완범-
dc.contributor.AlternativeAuthor박경운-
dc.contributor.AlternativeAuthor박상원-
dc.contributor.AlternativeAuthor송진수-
dc.contributor.AlternativeAuthor최평균-
dc.contributor.AlternativeAuthor전재현-
dc.contributor.AlternativeAuthor송경호-
dc.contributor.AlternativeAuthor김남중-
dc.contributor.AlternativeAuthor오명돈-
dc.contributor.AlternativeAuthor김홍빈-
dc.identifier.doi10.1136/sti.2009.037267-
dc.citation.journaltitleSEXUALLY TRANSMITTED INFECTIONS-
dc.description.citedreferenceKingston M, 2008, INT J STD AIDS, V19, P729, DOI 10.1258/ijsa.2008.008279-
dc.description.citedreferenceStoner BP, 2007, CLIN INFECT DIS, V44, pS130, DOI 10.1086/511426-
dc.description.citedreferenceWORKOWSKI KA, 2006, MMWR-MORBID MORTAL S, V55, P1-
dc.description.citedreferenceMarra CM, 2004, J INFECT DIS, V189, P369-
dc.description.citedreferenceCAREY LA, 1995, ARCH INTERN MED, V155, P1657-
dc.description.citedreferenceHOOK EW, 1992, NEW ENGL J MED, V326, P1060-
dc.description.citedreferenceMAY C, 1990, NEUROLOGY, V40, P500-
dc.description.citedreferenceLEFVERT AK, 1985, ANN NEUROL, V17, P13-
dc.description.citedreferencePRANGE HW, 1983, J NEUROL, V230, P241-
dc.description.tc0-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Laboratory Medicine (검사의학전공)Journal Papers (저널논문_검사의학전공)
Files in This Item:
There are no files associated with this item.
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse