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Aetiologies and outcomes of diffuse alveolar haemorrhage presenting as acute respiratory failure of uncertain cause

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dc.contributor.authorJin, Sang-Man-
dc.contributor.authorYim, Jae-Joon-
dc.contributor.authorYoo, Chul-Gyu-
dc.contributor.authorKim, Young-Whan-
dc.contributor.authorShim, Young-Soo-
dc.contributor.authorLee, Sang-Min-
dc.contributor.authorHan, Sung-Koo-
dc.date.accessioned2012-05-23T08:56:09Z-
dc.date.available2012-05-23T08:56:09Z-
dc.date.issued2009-03-
dc.identifier.citationRESPIROLOGY; Vol.14 2; 290-294ko_KR
dc.identifier.issn1323-7799-
dc.identifier.urihttps://hdl.handle.net/10371/76356-
dc.description.abstractConnective tissue diseases are the most common disorders causing diffuse alveolar haemorrhage (DAH) confirmed by open lung biopsy. However, it is not known whether these diseases are also the most common causes of DAH in patients presenting with the features of ARDS/acute lung injury (ALI). This study evaluated the frequency of concomitant disease in patients with ARDS/ALI and DAH. The sampling frame comprised all patients in a tertiary referral hospital diagnosed with ARDS/ALI and who underwent BAL between January 2000 and July 2006. The medical records of those patients who had BAL fluid findings compatible with DAH were reviewed. Of the 97 patients diagnosed with ARDS/ALI and who underwent BAL, 27 had BAL fluid findings compatible with DAH. Sixteen of the 27 patients did not have connective tissue diseases (59%); of these 12 patients had concomitant haematological malignancies or solid tumours. Of the seven patients who presented with DAH and no known underlying disease, only two were subsequently diagnosed with a connective tissue disorder. The in-hospital mortality rate was 55% and 63% for patients with DAH with and without connective tissue diseases, respectively (P = 0.710). The majority of patients with DAH presenting with the features of ARDS/ALI did not have underlying connective tissue diseases. Concomitant malignancies were found frequently in these patients. The outcome did not differ between patients with DAH with or without connective tissue diseases.ko_KR
dc.language.isoenko_KR
dc.publisherWILEY-BLACKWELL PUBLISHING, INCko_KR
dc.subjectacute lung injuryko_KR
dc.subjectintensive care unitko_KR
dc.subjectacute respiratory distress syndromeko_KR
dc.subjectbronchoalveolar lavageko_KR
dc.subjectdiffuse alveolar haemorrhageko_KR
dc.titleAetiologies and outcomes of diffuse alveolar haemorrhage presenting as acute respiratory failure of uncertain causeko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor진상만-
dc.contributor.AlternativeAuthor임재준-
dc.contributor.AlternativeAuthor유철규-
dc.contributor.AlternativeAuthor김영환-
dc.contributor.AlternativeAuthor한성구-
dc.contributor.AlternativeAuthor심영수-
dc.contributor.AlternativeAuthor이상민-
dc.identifier.doi10.1111/j.1440-1843.2008.01444.x-
dc.citation.journaltitleRESPIROLOGY-
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