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Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Cited 12 time in Web of Science Cited 15 time in Scopus
Authors
Park, Hyo Eun; Koo, Bon-Kwon; Lee, Wonjae; Cho, Youngjin; Choi, Ji-Yong; Kim, Jong Hyun; Kim, Young Jo; Lee, Jae-Hwan; Hong, Taek Jong; Park, Young Bae; Oh, Byung-Hee; Kim, Hyo-Soo; Kim, Kee Sik; Rhew, Jae Young; Chae, Jei Keon; Choi, Dong Hoon; Nam, Chang-Wook; Chae, Shung Chull; Jeong, Myung-Ho; Park, Jin Sik
Issue Date
2010-05
Publisher
JAPANESE CIRCULATION SOC
Citation
CIRCULATION JOURNAL; Vol.74 5; 970-976
Keywords
Acute myocardial infarctionPeriodic variationCircadian variation
Abstract
Background: The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. Methods and Results: From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203 +/- 288 min) compared with out-of-hours onset (230 +/- 288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patient`s and the medical facility`s response (door-to-balloon time out-of hours vs working hours: 101 54 min vs 84 44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) Conclusions: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes. (Circ J 2010; 74: 970-976)
ISSN
1346-9843
Language
English
URI
http://hdl.handle.net/10371/76544
DOI
https://doi.org/10.1253/circj.CJ-09-0344
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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