Browse

Thyroid Follicular Neoplasms: Can Sonography Distinguish between Adenomas and Carcinomas?

Cited 31 time in Web of Science Cited 32 time in Scopus
Authors
Seo, Hyung Suk; Lee, Dong Hoon; Park, Sung Hye; Min, Hye Sook; Na, Dong Gyu
Issue Date
2009-12
Publisher
JOHN WILEY & SONS INC
Citation
JOURNAL OF CLINICAL ULTRASOUND; Vol.37 9; 493-500
Keywords
ultrasonographyfollicular carcinomathyroidfollicular adenoma
Abstract
Purpose. The purpose of this study was to determine whether sonography (US) can usefully differentiate thyroid follicular adenoma (FA) and follicular carcinoma (FC). Methods. This retrospective study included 60 pathologically proven FAs and 66 FCs in 123 consecutive patients (17 males and 106 females) with a mean age of 47 +/- 13 years, (17-73 years) who underwent thyroid surgery. We analyzed US features of each nodule, including maximum diameter, echogenicity, composition, presence of calcification, margins, and presence of halo. The frequencies of each US feature were compared by using the chi(2) test or Fisher`s exact test between FAs and FCs. The relative risk of malignancy was evaluated by logistic regression analysis. Results. Isohypoechoic echogenicity, predominantly solid or mixed echotexture, and presence of microcalcifications or rim calcifications were associated with FC (p < 0.05). Logistic regression analysis demonstrated that predominantly solid or mixed echotexture and microcalcifications or rim calcifications were associated with significant increases in relative risk for FC (odds ratio 8.1 and odds ratio 13.5, respectively, p < 0.01). Conclusions. The US features of isohypoechoic echogenicity, predominantly solid or mixed echotexture, and microcalcifications or rim calcifications are more common in FC than in FA. (C) 2009 Wiley Periodicals, Inc J Clin Ultrasound 37:493-500, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI:10.1002/jcu.20625
ISSN
0091-2751
Language
English
URI
http://hdl.handle.net/10371/76619
DOI
https://doi.org/10.1002/jcu.20625
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Pathology (병리학전공)Journal Papers (저널논문_병리학전공)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse