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Impact of laparoscopic cystectomy on ovarian reserve: serial changes of serum anti-Mullerian hormone levels

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dc.contributor.authorChang, Hye Jin-
dc.contributor.authorHan, Sang Hoon-
dc.contributor.authorLee, Jung Ryeol-
dc.contributor.authorJee, Byung Chul-
dc.contributor.authorSuh, Chang Suk-
dc.contributor.authorKim, Seok Hyun-
dc.contributor.authorLee, Byoung Ick-
dc.date.accessioned2012-06-04T08:51:13Z-
dc.date.available2012-06-04T08:51:13Z-
dc.date.issued2010-06-
dc.identifier.citationFERTILITY AND STERILITY; Vol.94 1; 343-349ko_KR
dc.identifier.issn0015-0282-
dc.identifier.urihttp://hdl.handle.net/10371/76809-
dc.descriptionPresented at the 63rd Annual Meeting of the American Society for
Reproductive Medicine, Washington, DC, 13–17 October, 2007.
ko_KR
dc.description.abstractObjective: To evaluate the ovarian reserve changes after laparoscopic cystectomy, we prospectively evaluated pre- and postoperative serum anti-Mullerian hormone (AMH) level, and ovarian volumes. Design: Prospective longitudinal study. Setting: University Hospital. Patient(s): Twenty women with benign ovarian masses participated; endometrioma [13], mature teratoma [6], and mucinous cystadenoma [1]. Seven patients had bilateral ovarian masses. Intervention(s): All patients had undergone laparoscopic ovarian cystectomy. Serum AMH levels were serially measured: preoperative, 1 week, 1 month, and 3 months after operation. Volumes of total ovary and ovarian mass were measured by 3D ultrasonography before operation. Main Outcome Measure(s): Postoperative serum AMH level and ovarian volume. Result(s): Median AMH level was 2.23 ng/mL (95% confidence interval [CI] 1.35-3.41 ng/mL) before operation, but reduced to 0.67 ng/mL (95% CI 0.44-1.70 ng/mL) at the first week postoperatively and then increased to 1.14 ng/mL (95% CI 0.79-2.36 ng/mL) in the first month and 1.50 ng/mL (95% CI 0.58-3.26 ng/mL) in the third month. The serum AMH level after 3 months postoperatively was recovered to about 65% of the preoperative level. The serum AMH level at postoperative 1 week was more decreased in endometrioma compared with nonendometrioma (33.9% vs. 69.2% of preoperative level), and in bilateral group compared with unilateral group (16.9% vs. 62.9%). Conclusion(s): This study suggests that ovarian reserve could be reduced after laparoscopic cystectomy; however, it could be restored thereafter up to 3 months postoperative in reproductive women. (Fertil Steril (R) 2010; 94: 343-9. (C) 2010 by American Society for Reproductive Medicine.)ko_KR
dc.language.isoenko_KR
dc.publisherELSEVIER SCIENCE INCko_KR
dc.subjectOvarian reserveko_KR
dc.subjectovarian volumeko_KR
dc.subjectcystectomyko_KR
dc.subjectanti-Mullerian hormoneko_KR
dc.subject3D ultrasonographyko_KR
dc.titleImpact of laparoscopic cystectomy on ovarian reserve: serial changes of serum anti-Mullerian hormone levelsko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor장혜진-
dc.contributor.AlternativeAuthor한상훈-
dc.contributor.AlternativeAuthor이정렬-
dc.contributor.AlternativeAuthor조병철-
dc.contributor.AlternativeAuthor이병익-
dc.contributor.AlternativeAuthor서창석-
dc.contributor.AlternativeAuthor김석현-
dc.identifier.doi10.1016/j.fertnstert.2009.02.022-
dc.citation.journaltitleFERTILITY AND STERILITY-
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College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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