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Clinical Efficacy of Highly Purified hMG versus Recombinant FSH in IVF/ICSI Cycles: A Meta-Analysis

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dc.contributor.authorJee, Byung Chul-
dc.contributor.authorSuh, Chang Suk-
dc.contributor.authorKim, Yong Beom-
dc.contributor.authorKim, Seok Hyun-
dc.contributor.authorMoon, Shin Yong-
dc.date.accessioned2012-06-05T02:09:12Z-
dc.date.available2012-06-05T02:09:12Z-
dc.date.issued2010-
dc.identifier.citationGYNECOLOGIC AND OBSTETRIC INVESTIGATION; Vol.70 2; 132-137ko_KR
dc.identifier.issn0378-7346-
dc.identifier.urihttps://hdl.handle.net/10371/76832-
dc.description.abstractBackground/Aims: To compare the effectiveness of highly purified hMG (Menopur) with recombinant FSH (Gonal-F) in IVF/ICSI patients who underwent ovarian hyperstimulation with pituitary suppression. Methods: A literature search of the National Library of Medicine and the National Institutes of Health (PubMed), Medline and Cochrane Controlled Trials Register was performed using the key words `highly purified hMG` and `recombinant FSH.` Only prospective randomized controlled trials were included when they compared IVF/ICSI outcomes after administration of Menopur versus Gonal-F. Five studies met the inclusion criteria and were reviewed. The primary outcome measure was ongoing pregnancy/live birth. Results: Ongoing pregnancy rate per started cycle (RR: 1.10, 95% CI: 0.96-1.26) or per embryo transfer (RR: 1.13, 95% CI: 0.99-1.29), as well as live birth rate per embryo transfer (RR: 1.14, 95% CI: 0.98-1.33), is similar between the Menopur and the Gonal-F group. Conclusion: The combined data presented in this meta-analysis do not support a clinical superiority of Gonal-F over Menopur. Copyright (C) 2010 S. Karger AG, Baselko_KR
dc.language.isoenko_KR
dc.publisherKARGERko_KR
dc.subjectHighly purified hMGko_KR
dc.subjectMeta-analysisko_KR
dc.subjectPregnancy rateko_KR
dc.subjectRecombinant FSHko_KR
dc.subjectIVFko_KR
dc.titleClinical Efficacy of Highly Purified hMG versus Recombinant FSH in IVF/ICSI Cycles: A Meta-Analysisko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor지병철-
dc.contributor.AlternativeAuthor서창석-
dc.contributor.AlternativeAuthor김용범-
dc.contributor.AlternativeAuthor김석현-
dc.contributor.AlternativeAuthor문신용-
dc.identifier.doi10.1159/000308458-
dc.citation.journaltitleGYNECOLOGIC AND OBSTETRIC INVESTIGATION-
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