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Transmission of Seasonal Outbreak of Childhood Enteroviral Aseptic Meningitis and Hand-foot-mouth Disease

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dc.contributor.authorPark, Sue K.-
dc.contributor.authorPark, Boyoung-
dc.contributor.authorKi, Moran-
dc.contributor.authorKim, Ho-
dc.contributor.authorJung, Cheoll-
dc.contributor.authorChoi, Sung-Min-
dc.contributor.authorLee, Dong Seok-
dc.contributor.authorKim, Moon Kyu-
dc.contributor.authorCheong, Hae-Kwan-
dc.contributor.authorKo, Joon Tae-
dc.contributor.authorKim, Doo-Kwun-
dc.contributor.authorSohn, Young Mo-
dc.contributor.authorLee, Kwan-
dc.date.accessioned2012-06-08T00:43:26Z-
dc.date.available2012-06-08T00:43:26Z-
dc.date.issued2010-05-
dc.identifier.citationJOURNAL OF KOREAN MEDICAL SCIENCE; Vol.25 5; 677-683ko_KR
dc.identifier.issn1011-8934-
dc.identifier.urihttp://hdl.handle.net/10371/76897-
dc.description.abstractThis study was conducted to evaluate the modes of transmission of aseptic meningitis (AM) and hand-foot-mouth disease (HFMD) using a case-control and a case-crossover design. We recruited 205 childhood AM and 116 HFMD cases and 170 non-enteroviral disease controls from three general hospitals in Gyeongju, Pohang, and Seoul between May and August in both 2002 and 2003. For the case-crossover design, we established the hazard and non-hazard periods as week one and week four before admission, respectively. In the case-control design, drinking water that had not been boiled, not using a water purifier, changes in water quality, and contact with AM patients were significantly associated with the risk of AM (odds ratio [OR]=2.8, 2.9, 4.6, and 10.9, respectively), while drinking water that had not been boiled, having a non-water closet toilet, changes in water quality, and contact with HFMD patients were associated with risk of HFMD (OR=3.3, 2.8, 6.9, and 5.0, respectively). In the case-crossover design, many life-style variables such as contact with AM or HFMD patients, visiting a hospital, changes in water quality, presence of a skin wound, eating out, and going shopping were significantly associated with the risk of AM (OR=18.0, 7.0, 8.0, 2.2, 22.3, and 3.0, respectively) and HFMD (OR=9.0, 37.0, 11.0, 12.0, 37.0, and 5.0, respectively). Our findings suggest that person-to-person contact and contaminated water could be the principal modes of transmission of AM and HFMD.ko_KR
dc.language.isoenko_KR
dc.publisherKOREAN ACAD MEDICAL SCIENCESko_KR
dc.subjectMeningitis, Asepticko_KR
dc.subjectHand, Foot and Mouth Diseaseko_KR
dc.subjectWaterborne Infectionko_KR
dc.subjectEpidemiologyko_KR
dc.subjectEnterovirusko_KR
dc.subjectDisease Transmissionko_KR
dc.titleTransmission of Seasonal Outbreak of Childhood Enteroviral Aseptic Meningitis and Hand-foot-mouth Diseaseko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor박수경-
dc.contributor.AlternativeAuthor박보영-
dc.contributor.AlternativeAuthor기모란-
dc.contributor.AlternativeAuthor김호-
dc.contributor.AlternativeAuthor이관-
dc.contributor.AlternativeAuthor정철-
dc.contributor.AlternativeAuthor손영모-
dc.contributor.AlternativeAuthor최성민-
dc.contributor.AlternativeAuthor김두권-
dc.contributor.AlternativeAuthor이동석-
dc.contributor.AlternativeAuthor고준태-
dc.contributor.AlternativeAuthor김문규-
dc.contributor.AlternativeAuthor정해관-
dc.identifier.doi10.3346/jkms.2010.25.5.677-
dc.citation.journaltitleJOURNAL OF KOREAN MEDICAL SCIENCE-
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College of Medicine/School of Medicine (의과대학/대학원)Preventive Medicine (예방의학전공)Journal Papers (저널논문_예방의학전공)
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