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Non-invasive cortical stimulation improves post-stroke attention decline
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Eun Kyoung | - |
dc.contributor.author | Baek, Min Jae | - |
dc.contributor.author | Kim, SangYun | - |
dc.contributor.author | Paik, Nam-Jong | - |
dc.date.accessioned | 2012-06-18T06:31:37Z | - |
dc.date.available | 2012-06-18T06:31:37Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | RESTORATIVE NEUROLOGY AND NEUROSCIENCE; Vol.27 6; 647-652 | ko_KR |
dc.identifier.issn | 0922-6028 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77134 | - |
dc.description.abstract | Purpose: Attention decline after stroke is common and hampers the rehabilitation process, and non-invasive transcranial direct current stimulation (tDCS) has the potential to elicit behavioral changes by modulating cortical excitability. The authors tested the hypothesis that a single session of non-invasive cortical stimulation with excitatory anodal tDCS applied to the left dorsolateral prefrontal cortex (DLPFC) can improve attention in stroke patients. Methods: Ten patients with post-stroke cognitive decline (MMSE <= 25) and 10 age-matched healthy controls participated in this double blind, sham-controlled, crossover study involving the administration of real (2 mA for 20 min) or sham stimulation (2 mA for 1 min) to the left DLPFC. Attention was measured using a computerized Go/No-Go test before and after intervention. Improvements in accuracy and speed after stimulation relative to baseline were compared for real and sham stimulations. Results: In healthy controls, no significant improvement in Go/No-Go test was observed after either real or sham stimulation. However, in stroke patients, tDCS led to a significant improvement in response accuracy at 1 hour post-stimulation relative to baseline, and this improvement was maintained until 3 hours post-stimulation (P < 0.05), whereas sham stimulation did not lead to a significant improvement in response accuracy (P > 0.05). Changes in reaction times were comparable for the two stimulations (P > 0.05). Conclusion: Non invasive anodal tDCS applied to the left DLPFC was found to improve attention versus sham stimulation in stroke patients, which suggests that non-invasive cortical intervention could potentially be used during rehabilitative training to improve attention. | ko_KR |
dc.description.sponsorship | This research was supported by a grant from
Seoul National University College of Medicine (Grant No. 800-20060236) to N.J. Paik, and by a grant from the Korean Geriatric Society to E.K. Kang. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | IOS PRESS | ko_KR |
dc.subject | Attention | ko_KR |
dc.subject | cognition | ko_KR |
dc.subject | cortical stimulation | ko_KR |
dc.subject | tDCS | ko_KR |
dc.subject | stroke | ko_KR |
dc.title | Non-invasive cortical stimulation improves post-stroke attention decline | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 강은경 | - |
dc.contributor.AlternativeAuthor | 백민재 | - |
dc.contributor.AlternativeAuthor | 김상윤 | - |
dc.contributor.AlternativeAuthor | 백남종 | - |
dc.identifier.doi | 10.3233/RNN-2009-0514 | - |
dc.citation.journaltitle | RESTORATIVE NEUROLOGY AND NEUROSCIENCE | - |
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dc.description.tc | 7 | - |
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