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Association of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmatics

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dc.contributor.authorPark, Byung-Lae-
dc.contributor.authorPark, Se-Min-
dc.contributor.authorPark, Jong-Sook-
dc.contributor.authorUh, Soo-Taek-
dc.contributor.authorKim, Yong-Hoon-
dc.contributor.authorChoi, Inseon S.-
dc.contributor.authorCho, Sang-Heon-
dc.contributor.authorLee, Yong-Won-
dc.contributor.authorPark, Choon-Sik-
dc.contributor.authorShin, Hyoung-Doo-
dc.contributor.authorLee, Jae-Young-
dc.contributor.authorHong, Chein-Soo-
dc.contributor.authorChoi, Byoung-Whui-
dc.contributor.authorKim, Mi-Kgyeong-
dc.contributor.authorChoi, Jae-Sung-
dc.date.accessioned2012-06-25T04:36:56Z-
dc.date.available2012-06-25T04:36:56Z-
dc.date.issued2010-06-30-
dc.identifier.citationBMB REPORTS; Vol.43 6; 445-449ko_KR
dc.identifier.issn1976-6696-
dc.identifier.urihttps://hdl.handle.net/10371/77377-
dc.description.abstractAspirin-intolerant asthma (AIA) is characterized by severe asthmatic attack after ingestion of aspirin and/or non-steroidal anti-inflammatory drugs. In this study, we investigated the relationship between Prostaglandin E2 receptor (PTGER) gene family polymorphisms and AIA in 243 AIA patients and 919 aspirin-tolerant asthma (ATA) controls of Korean ethnicity in two separate study cohorts. After genotyping 120 SNPs of the PTGER gene family for the 1(st) cohort study, four SNPs in PTGER1, ten in PTGER3, six in PTGER3, and a haplotype of PTGER2 showed association signals with decreased or increased risk of AIA. Among the positively associated SNPs, one in PTGER1 and four in PTGER3 were analyzed in the 2(nd) cohort study. The results show that rs7543182 and rs959 in PTGER3 retained their effect, although no statistical significance was retained in the 2(nd) cohort study. Our findings provide further evidence that polymorphisms in PTGER3 might play a significant role in aspirin hypersensitivity among Korean asthmatics.ko_KR
dc.language.isoenko_KR
dc.publisherKOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGYko_KR
dc.subjectAspirin intolerant asthmako_KR
dc.subjectAsthmako_KR
dc.subjectProstaglandin E receptor(s)ko_KR
dc.subjectSingle nucleotide polymorphismko_KR
dc.titleAssociation of PTGER gene family polymorphisms with aspirin intolerant asthma in Korean asthmaticsko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor박병래-
dc.contributor.AlternativeAuthor박세민-
dc.contributor.AlternativeAuthor박종숙-
dc.contributor.AlternativeAuthor어수택-
dc.contributor.AlternativeAuthor최재성-
dc.contributor.AlternativeAuthor김용훈-
dc.contributor.AlternativeAuthor김미경-
dc.contributor.AlternativeAuthor최인선-
dc.contributor.AlternativeAuthor최병휘-
dc.contributor.AlternativeAuthor조상헌-
dc.contributor.AlternativeAuthor홍천수-
dc.contributor.AlternativeAuthor이용원-
dc.contributor.AlternativeAuthor이재영-
dc.contributor.AlternativeAuthor박준식-
dc.contributor.AlternativeAuthor신형두-
dc.identifier.doi10.5483/BMBRep.2010.43.6.445-
dc.citation.journaltitleBMB REPORTS-
dc.description.citedreferenceKim TH, 2008, CLIN EXP ALLERGY, V38, P1727, DOI 10.1111/j.1365-2222.2008.03082.x-
dc.description.citedreferencePark HW, 2007, CLIN EXP ALLERGY, V37, P1609, DOI 10.1111/j.1365-2222.2007.02820.x-
dc.description.citedreferenceKim SH, 2007, PHARMACOGENET GENOM, V17, P295, DOI 10.1097/01.fpc.0000239977.61841.fe-
dc.description.citedreferenceCormican LJ, 2005, CLIN EXP ALLERGY, V35, P717, DOI 10.1111/j.1365-2222.2005.02261.x-
dc.description.citedreferenceKunikata T, 2005, NAT IMMUNOL, V6, P524, DOI 10.1038/ni1188-
dc.description.citedreferenceJinnai N, 2004, HUM MOL GENET, V13, P3203, DOI 10.1093/hmg/ddh332-
dc.description.citedreferenceJenkins C, 2004, BRIT MED J, V328, P434-
dc.description.citedreferenceSzczeklik A, 2004, CURR OPIN PULM MED, V10, P51-
dc.description.citedreferencePierzchalska M, 2003, J ALLERGY CLIN IMMUN, V111, P1041, DOI 10.1067/mai.2003.1491-
dc.description.citedreferenceSzczeklik A, 2003, J ALLERGY CLIN IMMUN, V111, P913, DOI 10.1067/mai.2003.1487-
dc.description.citedreferenceBerges-Gimeno MP, 2002, ANN ALLERG ASTHMA IM, V89, P474-
dc.description.citedreferenceHigashi N, 2002, CLIN EXP ALLERGY, V32, P1484-
dc.description.citedreferenceOLIPHANT A, 2002, BIOTECHNIQUES, V32, pS56-
dc.description.citedreferenceConklin D, 2002, BIOINFORMATICS, V18, P182-
dc.description.citedreferencePicado C, 2002, ALLERGY, V57, P58-
dc.description.citedreferenceCelik G, 2001, CLIN EXP ALLERGY, V31, P1615-
dc.description.citedreferenceStephens M, 2001, AM J HUM GENET, V68, P978-
dc.description.citedreferenceStock JL, 2001, J CLIN INVEST, V107, P325-
dc.description.citedreferenceLam BK, 2000, AM J RESP CRIT CARE, V161, pS16-
dc.description.citedreferenceNarumiya S, 1999, PHYSIOL REV, V79, P1193-
dc.description.citedreferenceHedman J, 1999, INT J EPIDEMIOL, V28, P717-
dc.description.citedreferenceSzczeklik A, 1999, J ALLERGY CLIN IMMUN, V104, P5-
dc.description.citedreferenceLivak KJ, 1999, GENET ANAL-BIOMOL E, V14, P143-
dc.description.citedreferenceSampson A, 1998, THORAX, V53, P719-
dc.description.citedreferenceCowburn AS, 1998, J CLIN INVEST, V101, P834-
dc.description.citedreferenceVane JR, 1998, ANNU REV PHARMACOL, V38, P97-
dc.description.citedreferenceNEGISHI M, 1995, BBA-LIPID LIPID MET, V1259, P109-
dc.description.citedreferenceCOLEMAN RA, 1994, PHARMACOL REV, V46, P205-
dc.description.citedreferenceSNIJDEWINT FGM, 1993, J IMMUNOL, V150, P5321-
dc.description.citedreferenceBETZ M, 1991, J IMMUNOL, V146, P108-
dc.description.citedreferenceZEITZ HJ, 1988, CLIN CHEST MED, V9, P567-
dc.description.citedreferenceHEDRICK PW, 1987, GENETICS, V117, P331-
dc.description.citedreferenceLOEWE G, 1985, RHINOLOGY, V23, P19-
dc.description.citedreferenceSAMTER M, 1967, J ALLERGY, V40, P281-
dc.description.tc2-
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