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Secondary Appendiceal Tumors: A Review of 139 Cases

Cited 8 time in Web of Science Cited 6 time in Scopus
Authors
Yoon, Won Jae; Yoon, Yong Bum; Kim, Youn Joo; Ryu, Ji Kon; Kim, Yong-Tae
Issue Date
2010-09-30
Publisher
EDITORIAL OFFICE GUT & LIVER
Citation
GUT AND LIVER; Vol.4 3; 351-356
Keywords
NeoplasmsAppendixSecondary
Abstract
Background/Aims: This study evaluated the clinicopathologic characteristics of patients with secondary appendiceal tumors (SATs). Methods: We performed a single-center, retrospective study of patients with pathologically confirmed SATs. Results: Among 180 cases of appendiceal malignancies diagnosed between 2000 and 2007, 139 cases (77.2%, 46 male) were SATs. The median age at SAT diagnosis was 55 years. The most common primary origin was the ovary. The mode of appendiceal involvement was metastasis in 122 and invasion in 17 patients. Extra-appendiceal involvement was present in 134 patients. The only manifestation that could be attributed to the SAT itself was appendicitis (n=8). Serosal involvement was predominant. The median survival after diagnosis of SAT was 22.6 months. In the Cox regression analysis, chemotherapy included in the treatment was the only factor associated with prolonged survival (hazards ratio, 0.12; 95% confidence interval, 0.06-0.23; p<0.001). Complete resection of the SAT had no influence on survival. Conclusions: SATs accounted for 77.2% of all pathologically diagnosed appendiceal malignancies. The most common origin was the ovary. SATs were usually associated with widespread disease, and the median survival after SAT diagnosis was 22.6 months. Complete resection of the SAT had no influence on survival. (Gut Liver 2010;4:351-356)
ISSN
1976-2283
Language
English
URI
http://hdl.handle.net/10371/77597
DOI
https://doi.org/10.5009/gnl.2010.4.3.351
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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