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Association between colorectal adenoma and coronary atherosclerosis detected by CT coronary angiography in Korean men; a cross-sectional study

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dc.contributor.authorYang, Sun Young-
dc.contributor.authorKim, Young Sun-
dc.contributor.authorChung, Su Jin-
dc.contributor.authorSong, Ji Hyun-
dc.contributor.authorPark, Min Jung-
dc.contributor.authorLim, Seon Hee-
dc.contributor.authorKim, Chung Hyun-
dc.contributor.authorSong, In Sung-
dc.contributor.authorKim, Ju Sung-
dc.contributor.authorKim, Donghee-
dc.contributor.authorYim, Jeong Yoon-
dc.contributor.authorChoi, Su Yeon-
dc.date.accessioned2012-06-27T08:53:59Z-
dc.date.available2012-06-27T08:53:59Z-
dc.date.issued2010-11-
dc.identifier.citationJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY; Vol.25 11; 1795-1799ko_KR
dc.identifier.issn0815-9319-
dc.identifier.urihttp://hdl.handle.net/10371/77660-
dc.description.abstractBackground: Colorectal adenoma and coronary artery disease (CAD) appear to share common risk factors, such as male gender, diabetes mellitus, smoking, and obesity. We investigated the relationship between colorectal adenoma and coronary atherosclerosis, as a risk factor for colorectal adenoma. Methods: A cross-sectional study was conducted on Korean men who presented for a health check-up. The subjects were 488 men (217 colorectal adenoma and 271 normal colonoscopic findings) who underwent colonoscopy and coronary computed tomography angiography (CTA) on the same day as a screening examination. Advanced colonic lesion was defined as a presence of adenoma with villous component, high-grade dysplasia, and/or with size of >= 1 cm. CTA findings were classified as normal, mild (low-grade atherosclerosis or < 50% stenosis), and significant CAD (>= 50% stenosis). Abnormal CTA findings included mild and significant CAD. Results: Patients with abnormal CTA findings were more likely to have colorectal adenoma compared with those with normal CTA findings (P < 0.005). Furthermore, presence of advanced adenoma was significantly associated with significant CAD (P < 0.01). On multivariate analyses, abnormal CTA findings (OR = 1.66, 95% CI: 1.14-2.41, P < 0.01) and significant CAD (OR = 1.96, 95% CI: 1.15-3.35, P < 0.05) were found to be independent risk factors for colorectal adenoma after adjusting for age, current smoking, and metabolic syndrome. Conclusions: In this study, in the population who underwent CTA and colonoscopy for health check-up, prevalence of colorectal adenoma was greater in subjects with low-grade coronary atherosclerosis or significant CAD. The presence of advanced adenoma was significantly associated with significant CAD.ko_KR
dc.language.isoenko_KR
dc.publisherWILEY-BLACKWELLko_KR
dc.subjectcolorectal adenomako_KR
dc.subjectcoronary angiographyko_KR
dc.subjectcomputed tomographyko_KR
dc.subjectcoronary atherosclerosisko_KR
dc.subjectrisk factorko_KR
dc.subjectcoronary artery diseaseko_KR
dc.titleAssociation between colorectal adenoma and coronary atherosclerosis detected by CT coronary angiography in Korean men; a cross-sectional studyko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor양선영-
dc.contributor.AlternativeAuthor김영순-
dc.contributor.AlternativeAuthor정수진-
dc.contributor.AlternativeAuthor송지현-
dc.contributor.AlternativeAuthor최수연-
dc.contributor.AlternativeAuthor박민정-
dc.contributor.AlternativeAuthor임정윤-
dc.contributor.AlternativeAuthor임선희-
dc.contributor.AlternativeAuthor김동희-
dc.contributor.AlternativeAuthor김정현-
dc.contributor.AlternativeAuthor김주성-
dc.contributor.AlternativeAuthor송인성-
dc.identifier.doi10.1111/j.1440-1746.2010.06330.x-
dc.citation.journaltitleJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY-
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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