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Cardiovascular Diseases after Kidney Transplantation in Korea

Cited 13 time in Web of Science Cited 14 time in Scopus
Authors
Jeong, Jong Cheol; Ro, Han; Hwang, Young-Hwan; Lee, Han Kyu; Ahn, Curie; Yang, Jaeseok; Ha, Jongwon
Issue Date
2010-11
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE; Vol.25(11); 1589-1594
Keywords
Cardiovascular DiseasesKoreansDiabetes MellitusIncidenceKidney TransplantationRisk Factors
Abstract
Cardiovascular disease (CVD) is the leading cause of death in renal allograft recipients with functioning graft. Our study aimed to determine the incidence and the risk factors of cardiovascular disease after renal transplantation in Korea. We retrospectively analyzed 430 adult recipients who underwent kidney transplantation between January 1997 and February 2007. CVD was defined as a composite outcome of ischemic heart disease, cerebrovascular accident and peripheral vascular disease. Mean age of recipients was 40.0+/-11.8 yr. Mean duration of follow-up was 72+/-39 months. The cumulative incidence of CVD after renal transplantation was 2.4% at 5 yr, 5.4% at 10 yr and 11.4% at 12 yr. Multivariate analysis revealed that recipient`s age, diabetes mellitus and duration of dialysis before transplantation were associated with post-transplant CVD (hazard ratio 1.843 [95% CI, 1.005-3.381], 3.846 [95% CI, 1.025-14.432] and 3.394 [95% CI, 1.728-6.665] respectively). In conclusion, old age, duration of dialysis and diabetes mellitus are important risk factors for post-transplant CVD, although the incidence of post-renal transplant CVD is lower in Korea than that in western countries.
ISSN
1011-8934
Language
English
URI
http://hdl.handle.net/10371/77935
DOI
https://doi.org/10.3346/jkms.2010.25.11.1589
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College of Medicine/School of Medicine (의과대학/대학원)Surgery (외과학전공)Journal Papers (저널논문_외과학전공)
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