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Keratoacanthoma aggravated after photodynamic therapy

Cited 7 time in Web of Science Cited 7 time in Scopus
Authors
Yeon, Je Ho; Jung, Jae Yoon; Choi, Jee Woong; Kim, Beom Joon; Youn, Sang Woong; Huh, Chang Hun; Park, Kyung Chan; Lee, Ju Hee
Issue Date
2010-08
Publisher
WILEY-BLACKWELL
Citation
JOURNAL OF DERMATOLOGY; Vol.37(8); 765-766
Abstract
Keratoacanthoma (KA) is a relatively common epithelial
tumor and may develop at sites of previous
trauma. Most cases grow rapidly then undergo spontaneous
regression, leaving an atrophic scar. But
some cases of KA cause destructive variants without
regression and persistent invasive growth.
A 54-year-old man first visited our hospital with a
tumor on ala of the nose. The tumor developed
4 months prior, grew in the first 2 months and stopped
growing in next 2 months. The tumor was 1 cm in
diameter at first visit, and was an exophytic, well
demarcated and erythematous nodule with central
keratotic plug (Fig. 1a) and KA was proved by
histopathological examination. The patient refused to
undergo surgical procedure because he was worried
about it leaving scars on his face after surgery. Therefore,
we decided to perform topical photodynamic
therapy (PDT). Methyl aminolevulinate (MAL) cream
(Metvix; Galderma, Paris, France) applied to the tumor
under occlusion for 3 h.
ISSN
0385-2407
Language
English
URI
http://hdl.handle.net/10371/78330
DOI
https://doi.org/10.1111/j.1346-8138.2010.00876.x
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College of Medicine/School of Medicine (의과대학/대학원)Dermatology (피부과학전공)Journal Papers (저널논문_피부과학전공)
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