S-Space College of Medicine/School of Medicine (의과대학/대학원) Radiology (영상의학전공) Journal Papers (저널논문_영상의학전공)
Microheater based on magnetic nanoparticle embedded PDMS
- Kim, Jeong Ah; Lee, Seung Hwan; Park, Hongsuk; Kim, Jong Hyo; Park, Tai Hyun
- Issue Date
- IOP PUBLISHING LTD
- NANOTECHNOLOGY; Vol.21 16; 165102 (7pp)
- A microheater was established by embedding magnetic nanoparticles into PDMS (MNP-PDMS). MNP-PDMS generated heat under an AC magnetic field and the temperature was controlled by varying the magnetic particle content and the magnetic field intensity. In this study, the MNP-PDMS chip was demonstrated to amplify the target DNA (732 bp) with >90% efficiency compared to the conventional PCR thermocycler, and exhibited good performance in regards to temperature control. This system holds great promise for reliably controlling the temperature of thermal processes on an integrated microchip platform for biochemical applications.
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