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Differential pattern of heart rate variability in patients with schizophrenia
DC Field | Value | Language |
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dc.contributor.author | Chang, Jae Seung | - |
dc.contributor.author | Yoo, Cheol Sung | - |
dc.contributor.author | Yi, Sang Hoon | - |
dc.contributor.author | Hong, Kye Hyun | - |
dc.contributor.author | Hwang, Jae Youn | - |
dc.contributor.author | Ahn, Yong Min | - |
dc.contributor.author | Kim, Yong Sik | - |
dc.contributor.author | Kim, Su-Gyeong | - |
dc.contributor.author | Oh, Hong Seok | - |
dc.date.accessioned | 2012-07-05T04:09:50Z | - |
dc.date.available | 2012-07-05T04:09:50Z | - |
dc.date.issued | 2009-08-31 | - |
dc.identifier.citation | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY; Vol.33 6; 991-995 | ko_KR |
dc.identifier.issn | 0278-5846 | - |
dc.identifier.uri | https://hdl.handle.net/10371/78575 | - |
dc.description.abstract | The cardiac autonomic dysfunction has been reported in patients with schizophrenia. Heart rate variability (HRV) provides non-invasive indices of cardiac autonomic modulation. This study examined whether patients with schizophrenia may show a distinctive pattern of HRV compared to healthy controls. Nine measures of time, frequency and complexity domains were extracted from 5-min resting evaluation of HRV in 30 unmedicated patients with schizophrenia and 30 age- and gender-matched controls. In addition to inferential statistics, a hierarchical clustering (HC) was used to examine difference in the interrelationships among HRV measures between the two groups. Multivariate analysis of variance revealed a significant group effect. Significantly lower sample entropy (SampEn) and a trend towards a higher ratio of low- to high frequency (LF/HF) were observed in the schizophrenia group. In the results of HC using Ward`s method. SampEn co-clustered with LF/HF ratio in patients with schizophrenia compared to the separation of LF/HF ratio in healthy controls. In concert with decreased parasympathetic activity. low complexity of heart rate dynamics may reduce adaptability of cardiovascular system to changes in internal or external environment, thus increasing the risk of cardiovascular events. Diverse HRV measures combined in a multivariate fashion appear to be useful in understanding the pattern of neurocardiac modulation in patients with schizophrenia. (C) 2009 Elsevier Inc. All rights reserved. | ko_KR |
dc.description.sponsorship | This study was supported by Grant No. 09-2003-009 from Seoul
National University Hospital and Grant No. M103KV010012-06K2201- 01210 from the Brain Research Center of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology, Republic of Korea. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | ko_KR |
dc.subject | Complexity | ko_KR |
dc.subject | Heart rate variability | ko_KR |
dc.subject | Schizophrenia | ko_KR |
dc.subject | Hierarchical clustering | ko_KR |
dc.title | Differential pattern of heart rate variability in patients with schizophrenia | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 장재승 | - |
dc.contributor.AlternativeAuthor | 유철성 | - |
dc.contributor.AlternativeAuthor | 이상훈 | - |
dc.contributor.AlternativeAuthor | 홍계현 | - |
dc.contributor.AlternativeAuthor | 오홍석 | - |
dc.contributor.AlternativeAuthor | 황재윤 | - |
dc.contributor.AlternativeAuthor | 김수경 | - |
dc.contributor.AlternativeAuthor | 안용민 | - |
dc.contributor.AlternativeAuthor | 김용식 | - |
dc.identifier.doi | 10.1016/j.pnpbp.2009.05.004 | - |
dc.citation.journaltitle | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | - |
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dc.description.tc | 7 | - |
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