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Thymosin beta 4 enhances NK cell cytotoxicity mediated by ICAM-1

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dc.contributor.authorLee, Ha-reum-
dc.contributor.authorYoon, Sun Young-
dc.contributor.authorKang, Ho-Bum-
dc.contributor.authorPark, Sunyoung-
dc.contributor.authorCho, Young Hoon-
dc.contributor.authorKim, Chul-woo-
dc.contributor.authorLee, Wang Jae-
dc.contributor.authorPark, Hyunjeong-
dc.contributor.authorCho, Daeho-
dc.contributor.authorBang, Sa Ik-
dc.contributor.authorCho, Byung Joo-
dc.contributor.authorKim, Seonghan-
dc.contributor.authorKim, Kyung-Eun-
dc.date.accessioned2012-07-09T08:27:28Z-
dc.date.available2012-07-09T08:27:28Z-
dc.date.issued2009-03-24-
dc.identifier.citationIMMUNOLOGY LETTERS; Vol.123(1); 72-76ko_KR
dc.identifier.issn0165-2478-
dc.identifier.urihttp://hdl.handle.net/10371/78667-
dc.description.abstractThymosin beta 4 (T beta 4), which is the major G-actin sequestering protein, has been shown to have ubiquitous distribution and multiple biological activities. However, T beta 4`s functions in relation to natural killer (NK) cells are still unknown. In this study, we show that synthetic T beta 4 peptide increases NK cell cytotoxicity mediated by intercellular adhesion molecule-1 (ICAM-1) through the secretion of cytolytic granules to target cells. This suggests that T beta 4 is a key activator of NK cell cytotoxicity.ko_KR
dc.language.isoenko_KR
dc.publisherELSEVIER SCIENCE BVko_KR
dc.subjectThymosin beta 4ko_KR
dc.subjectNK cell cytotoxicityko_KR
dc.subjectICAM-1ko_KR
dc.titleThymosin beta 4 enhances NK cell cytotoxicity mediated by ICAM-1ko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor이하름-
dc.contributor.AlternativeAuthor윤선영-
dc.contributor.AlternativeAuthor강호범-
dc.contributor.AlternativeAuthor박선영-
dc.contributor.AlternativeAuthor김경은-
dc.contributor.AlternativeAuthor조영훈-
dc.contributor.AlternativeAuthor김성한-
dc.contributor.AlternativeAuthor김철우-
dc.contributor.AlternativeAuthor조병주-
dc.contributor.AlternativeAuthor이왕재-
dc.contributor.AlternativeAuthor방사익-
dc.contributor.AlternativeAuthor박현정-
dc.contributor.AlternativeAuthor조대호-
dc.identifier.doi10.1016/j.imlet.2009.02.008-
dc.citation.journaltitleIMMUNOLOGY LETTERS-
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College of Medicine/School of Medicine (의과대학/대학원)Anatomy (해부학전공)Journal Papers (저널논문_해부학전공)
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