Ehrlichia chaffeensis Infection in Dogs in South Korea

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Yu, Do-Hyeon; Li, Ying-Hua; Yoon, Ji-Seon; Lee, Jong-Hyeon; Lee, Mi-Jin; Yu, Il-Jeoung; Chae, Joon-seok; Park, Jin-Ho
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Mary Ann Liebert
Vector-Borne Zoonotic Dis 2008; 8:355-358
Ehrlichia chaffeensisDogPCRKorea
Ehrlichia chaffeensis is one of the causative agents of canine ehrlichiosis and human monocytic ehrlichiosis (HME).
Canine ehrlichiosis caused by E. chaffeensis was diagnosed in two dogs in South Korea based on clinical findings,
and the diagnosis was confirmed by polymerase chain reaction (PCR) and DNA sequencing. A 5-year-old
intact male American Pit bull terrier allowed outdoors was found to be concurrently infected with Babesia gibsoni
and E. chaffeensis. The major clinical findings were lethargy and reddish urine, and laboratory analysis revealed
severe hematuria and thrombocytopenia. In addition, a 3-year-old neutered male Shih-tzu was also found
to be infected with E. chaffeensis. Although this dog was an indoor companion animal, he was frequently allowed
outside for exercise. The clinical signs observed in this dog included generalized purpura with petechiae and ecchymoses
due to thrombocytopenia. A 390-bp partial portion of E. chaffeensis 16S rRNA gene was amplified in
both cases, and nucleotide sequence analysis revealed 99% homology of this fragment with other E. chaffeensis
isolates. These findings demonstrate the presence of E. chaffeensis infection in dogs in South Korea, and this is
the first report to confirm clinical cases of E. chaffeensis infection in dogs.
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College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
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