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Reduced Immunoreactivity of Tyrosine Hydroxylase in the Hypothalamic Paraventricular Nucleus of the Seizure Sensitive Gerbil

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Authors
Lee, Choong Hyun; Choi, Jung Hoon; Chung, Dae Won; Hwang, In Koo; Yoon, Yeo Sung; Won, Moo-Ho; Lee, In Se
Issue Date
2008
Publisher
Japanese Society of Veterinary Science
Citation
J. Vet. Med. Sci. 70: 645-648
Keywords
Mongolian gerbilseizureTyrosine hydroxylase
Abstract
We compared the immunoreactivity and numbers of tyrosine hydroxylase (TH) immunoreactive neurons and neuropil in the
paraventricular nucleus (PVN) of the hypothalamus between the seizure sensitive (SS) and seizure resistant (SR) gerbils. The distributional
pattern of TH immunoreactivity was similar in both groups: TH immunoreactivity was seen mainly in magnocellular neurons of
the PVN. However, total TH immunoreactivity in the neurons and neuropil in the SS gerbils was significantly lower than that in the SR
gerbils. In addition, the number of TH immunoreactive neurons in the SS gerbils was also much lower than those in the SR gerbils.
These results indicate that SS gerbils have a low TH immunoreactivity in the hypothalamic PVN compared with that in SR gerbils.
ISSN
0916-7250 (print)
1347-7439 (online)
Language
English
URI
http://hdl.handle.net/10371/7901
DOI
https://doi.org/10.1292/jvms.70.645
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College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
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