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A Suprachoroidal Electrical Retinal Stimulator Design for Long-Term Animal Experiments and
Cited 61 time in
Web of Science
Cited 70 time in Scopus
- Authors
- Issue Date
- 2008-02
- Publisher
- Hindawi Publishing Corporation
- Citation
- Journal of Biomedicine and Biotechnology, vol. 2008, Article ID 547428, 2008
- Abstract
- This article reports on a retinal stimulation system for long-term use in animal electrical stimulation experiments. The presented
system consisted of an implantable stimulator which provided continuous electrical stimulation, and an external component which
provided preset stimulation patterns and power to the implanted stimulator via a paired radio frequency (RF) coil. A rechargeable
internal battery and a parameter memory component were introduced to the implanted retinal stimulator. As a result, the external
component was not necessary during the stimulation mode. The inductive coil pair was used to pass the parameter data and to
recharge the battery. A switch circuit was used to separate the stimulationmode fromthe battery recharging mode. The implantable
stimulator was implemented with IC chips and the electronics, except for the stimulation electrodes, were hermetically packaged
in a biocompatible metal case. A polyimide-based gold electrode array was used. Surgical implantation into rabbits was performed
to verify the functionality and safety of this newly designed system. The electrodes were implanted in the suprachoroidal space.
Evoked cortical potentials were recorded during electrical stimulation of the retina. Long-term follow-up using OCT showed no
chorioretinal abnormality after implantation of the electrodes.
- ISSN
- 1110-7251
- Language
- English
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