Publications
Detailed Information
토끼 콩팥의 혈액유통에 대한 막네슘의 구실 : The Role of Magnesium on the Renal Blood flow in Rabbit Kidney
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 고일섭 | - |
dc.date.accessioned | 2009-08-31T11:57:13Z | - |
dc.date.available | 2009-08-31T11:57:13Z | - |
dc.date.issued | 1964-03-01 | - |
dc.identifier.citation | Seoul J Med, Vol.5 No.1, pp. 63-69 | - |
dc.identifier.issn | 0582-6802 | - |
dc.identifier.uri | https://hdl.handle.net/10371/8172 | - |
dc.description.abstract | The relationship of pressure to flow was studied
in the renal vascular bed of the isolated rabbit kidneys which were perfused with various solutions containing cations under various levels of perfusion pressure. Magnesium and calcium ions in normal saline solution were perfused into the renal artery. Three isolated dog and 39 rabbit kidneys were used. The following results were obtained. 1) There was autoregulation of flow in the isolated dog kidneys perfused with Tyrode's solution without dextran. 2) There was no autoregulation of renal blood flow in the isolated rabbit kidneys perfused with Tyrode's or Locke's solution without dextran. 3) The renal blood flow was autoregulated in the isolated rabbit kidneys when the magnesium chloride in isotonic saline was perfused. It was discussed that magnesium ions affected the contractility of the renal vascular smooth muscle. 4) The autoregulation of flow which was induced by perfusion of magnesium ions was abolished by addition of calcium ions. Magnesium and calcium ions seemed to have an antagonistic effects upon the smooth muscles of the renal vascular bed. 5) In the pressure-flow relationship, a change in perfusion pressure always resulted in a corresponding change in the renal blood flow when the isolated rabbit kidneys were perfused with calcium chloride in isotonic saline solution. 6) The pressure-flow pattern was not significantly different from each other when magnesium-added fluid was given with or without oxygenation. 7) It is concluded that autoregulation of the renal blood flow is attributable to the sensitivity of vascular smooth muscles to the change in tension of the wall of the blood vessel. (The author was indebted to Dr. H. Passow, of the Department of Physiology, University of Hamburg, Germany, for his advice in the early stages of this study, and to Professor Dr. K. Y. Nam for valuable advice and guidance.) | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 의과대학 | - |
dc.title | 토끼 콩팥의 혈액유통에 대한 막네슘의 구실 | - |
dc.title.alternative | The Role of Magnesium on the Renal Blood flow in Rabbit Kidney | - |
dc.type | SNU Journal | - |
dc.contributor.AlternativeAuthor | Koh, Il Sup | - |
dc.citation.journaltitle | 서울 의대 잡지 | - |
dc.citation.journaltitle | 서울 의대 학술지 | - |
dc.citation.journaltitle | Seoul Journal of Medicine | - |
dc.citation.endpage | 69 | - |
dc.citation.number | 1 | - |
dc.citation.pages | 63-69 | - |
dc.citation.startpage | 63 | - |
dc.citation.volume | 5 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.