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Health-related quality of life in disease-free survivors of breast cancer with the general population

Cited 103 time in Web of Science Cited 110 time in Scopus
Authors
Ahn, S. H.; Park, B. W.; Noh, D. Y.; Nam, S. J.; Lee, E. S.; Lee, M. K.; Kim, S. H.; Lee, K. M.; Park, S. M.; Yun, Y. H.
Issue Date
2007-01
Publisher
Oxford University Press
Citation
ANNALS OF ONCOLOGY Vol.18 No.1, pp. 173-182
Keywords
의약학breast cancerdisease-free survivorhealth-related quality of life
Abstract
Background: Although most of the literature about health-related quality of life (HRQoL) focuses on breast cancer patients, few studies compared the HRQoL in disease-free breast cancer survivors with that of the general population. Materials and methods: We administered the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and Quality of Life Questionnaire Breast Cancer Module, McGill Quality of Life Questionnaire, Beck Depression Inventory, and Brief Fatigue Inventory to 1933 disease-free survivors for over 1 year after being diagnosed with stage 0 to III breast cancer. We performed multivariate-adjusted analyses in all HRQoL comparisons. Results: The scores for some HRQoL scales were comparable for both disease-free breast cancer survivors and the general female population; however, there was clinically significant difference in cognitive and social functioning, fatigue, insomnia, and financial difficulties between the two groups. Radiotherapy and systemic adjuvant therapy variables did not limit the HRQoL. Demographic characteristics such as age, time since surgery, and comorbidity were associated with some HRQoL scales and fatigue and depression were associated with almost all HRQoL scales. Conclusions: Disease-free survivors of breast cancer had good HRQoL, which was less affected by the type of treatment than it was by demographic characteristics, time since surgery, comorbidity, fatigue, and depression.
ISSN
0923-7534
Language
English
URI
http://hdl.handle.net/10371/81797
DOI
https://doi.org/10.1093/annonc/mdl333
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)Journal Papers (저널논문_의학과)
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