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Identifying the Viral Genes Encoding Envelope Glycoproteins for Differentiation of Cyprinid herpesvirus 3 Isolates

Cited 8 time in Web of Science Cited 9 time in Scopus
Authors

Han, Jee Eun; Kim, Ji Hyung; Renault, Tristan; Choresca Jr., Casiano; Shin, Sang Phil; Jun, Jin Woo; Park, Se Chang

Issue Date
2013-02
Publisher
MDPI AG
Citation
VIRUSES-BASEL Vol.2013 No.5, pp. 568-576
Keywords
농수해양Cyprinid herpes virus 3glycoprotein geneKoi herpesvirusmicrosatellitepolymorphismphylogenetic tree
Abstract
Cyprinid herpes virus 3 (CyHV-3) diseases have been reported around the world and are associated with high mortalities of koi (Cyprinus carpio). Although little work has been conducted on the molecular analysis of this virus, glycoprotein genes identified in the present study seem to be valuable targets for genetic comparison of this virus. Three envelope glycoprotein genes (ORF25, 65 and 116) of the CyHV-3 isolates from the USA, Israel, Japan and Korea were compared, and interestingly, sequence insertions or deletions were observed in these target regions. In addition, polymorphisms were presented in microsatellite zones from two glycoprotein genes (ORF65 and 116). In phylogenetic tree analysis, the Korean isolate was remarkably distinguished from USA, Israel, Japan isolates. These findings may be suitable for many applications including isolates differentiation and phylogeny studies.
ISSN
1999-4915
Language
English
URI
https://hdl.handle.net/10371/82003
DOI
https://doi.org/10.3390/v5020568
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College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
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