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동질 임파조직 및 Adjuvant 반복주사백서의 임파결절 병변에 관한 병리조직학적 연구 : Morphologic Changes of the Lymphnodes Following the Repeated Injections of the Homologous Homogenized Lymphnodes
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- Authors
- Issue Date
- 1970-03-01
- Publisher
- 서울대학교 의과대학
- Citation
- Seoul J Med, Vol.11 No.1, pp. 49-61
- Abstract
- In order to clarify the nature and significance of the
so-called autoimmune diseases, the morphologic changes
of the lymphnodes of the rats following the
repeated injections of the homologous homogenized
lymphnodes with or without Freund's adjuvant, were
studied.
The results were as follows:
1. The mesenteric lymphnodes of the rats received
repeated injections of the homologous homogenized
lymphnodes and Freund's adjuvant revealed rather
marked changes, namely, proliferation of the reticuloendothelial
cells in the cortex and medulla, aggregation
of histiocytes, collections or infiltration of lymphocytes,
large mononuclear cells and plasma cells in
intra- or inter-sinusoidal spaces, and thickening of
the small blood vessels, while the similar but milder
chages were also observed in the lymph nodes of the rats
received thehomogenized lymphnodes or adjuvant only.
2. The repeated injections of the homogenized liver
were followed not only by the marked infiltration of
- ISSN
- 0582-6802
- Language
- Korean
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