SHERP

포도구균 및 대장균 혼합감염증에 있어서 도입경로의 차이가 미치는 영향에 관한 실험적연구
Influences of the Different Inoculation Routes on the Experimental Mixed Infections of Staphyflococcus Aureus and Escherichia Coli.

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Authors
이승달
Issue Date
1970-12-01
Publisher
서울대학교 의과대학
Citation
Seoul J Med 1970;11(4):1-10
Abstract
It is well known that the different inoculation routes
might produce quite different outcome of infections.
However, comparisons of microbial virulences in
different inoculation routes have been done so far by
inoculating single species of microorganisms. Lately
reports were published that the relative incidence of
mixed infections increased considerably.
Thus, it was conceived worthwhile to study the
influences of the different inoculation routes on the
experimental mixed infections. Staph. au reus and Es.
coli were cultivated and inoculated into rabbits ear
vein and peritoneal cavity, mixed or separately.
Viable units of both microbial species in the heart
blood and bladder urine were followed.
Results were summarized as follows:
1. When the suspensions of Staph. aureus and Es.
coli were mixed and inoculated intravenously;
The viable units of staphylococci in the blood stream
decreased rather slowly during the period of 3hours
to 7days of infction.
The viable units of staphylococci in the bladder
urine increased sharply until 3-to 5days of infection
and decreased later on.
Small number of colon bacilli were recovered intermittently
from the blood stream.
The viable units of colon bacilli in the urine showed
some increase until Iday after inoculation, followed
hy no noticiable increase or decrease until 3day, and
then showed marked increase until 7day of infection.
2. When the suspension of Staph. au reus and Es.
coli were mixed and inoculated intraperitoneally ;
From the blood stream no viable unit of staphylococci
or colon bacilli was recovered through the 7days
of observation.
9
Viable units of staphylococci in the urine showed
some increase until 2nd day and then no noticiable
increase or decrease until 7th day.
Duringl to 3days of infection small number of colon
bacilli were recovered from the urine, but could not
be recovered after 3to 5days.
3. When the staphylococci were inoculated intravenously
and colon bacilli intraperitoneally;
The viable units of staphylococci in the blood showed
sharp increase for 1 to 2 days and after that no
noticiable decrease or increase until 7th day.
The viable units of staphylococci in the urine showed
sharp increase for 1 to 3days and no noticiable
incroase or decerase until 7th day.
Except very small number of colon bacilli ater
3hour, no colon bacillus could be recovered through
7days.
After 2days the colon bacilli in the utine increased
markedly until 5th and decreased.
4. When the colon bacilli were inoculated intravenously
and the staphylococci intraperitoneally;
No staphylococcus was recovered from the blood
through 7days of observations, but small number of
staphylocecci were recovered sporadiccally from the
urine.
Small number of colon bacilli were recovered from
the blood persistently.
Viable units of colon bacilli in the urine increased
sharply for 1 to 2 days. followed no noticiable
increase ordecrease until 5th day, and then decreased.
Language
Korean
URI
http://hdl.handle.net/10371/8230
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 11 No.3 (1970)
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