Browse

Antimicrobial activity of magnolol and honokiol against periodontopathic microorganisms

Cited 59 time in Web of Science Cited 70 time in Scopus
Authors
Chang, Beom Seok; Lee, Yong Moo; Ku, Young; Bae, Ki Hwan; Chung, Chong Pyoung
Issue Date
1998
Publisher
Georg Thieme Verlag
Citation
Planta Medica Vol.64, No.4, pp.367-369
Abstract
Magnolol (1) and honokiol (2), main compounds from the stem bark of Magnolia obovata Thunb., were evaluated for an antimicrobial activity against periodontopathic microorganisms, Porphyromonas gingivalis, Prevotella gingivalis, Actinobacillus actinomycetemcomitans, Capnocytophaga gingivalis, and Veillonella disper, and a cytotoxicity against human gingival fibroblasts and epithelial cells. Our results indicate that magnolol and honokiol, although less potent than chlorhexidine, show a significant antimicrobial activity against these microorganisms, and a relatively low cytotoxic effect on human gingival cells. Thus, it is suggested that magnolol and honokiol may have a potential therapeutic use as a safe oral antiseptic for the prevention and the treatment of periodontal disease.
ISSN
0032-0943
Language
English
URI
http://hdl.handle.net/10371/82356
DOI
https://doi.org/10.1055/s-2006-957453
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse